Protein Alignment east and srrm2

DIOPT Version :9

• Sequence 1: NP_001245484.1
• Gene: east / 46006
• FlyBaseID: FBgn0261954
• Length: 2342
• Species: Drosophila melanogaster
• Sequence 2: NP_001025246.2
• Gene: srrm2 / 553531
• ZFINID: ZDB-GENE-050522-399
• Length: 1282
• Species: Danio rerio
• Alignment Length: 1394
• Identity: 257/1394 - (18%)
• Similarity: 427/1394 - (30%)
• Gaps: 457/1394 - (32%)

  Fly     3 SRKVPGGSGGADESTAAAAPLDDNANASV--------------EIPDSSEEPAMGVGEEMSIISK 53
            :|...||.....:.....:.|:...||.:              |:.|..||......|   |..|
Zfish    31 NRDERGGERDEKDKERLESQLNRQPNADILEHQRKRQLEVKCAELQDMMEEQGYSAEE---IEEK 92

  Fly    54 TRTSTLSVEPAKEPTVTAELEGEKELESNPVSKTPRSTPTPTLTPAVTPTASDGVA--AKSVRVT 116
            ..|..|.::..:||                       .|.||...|||.|.:...|  .|:.|:
Zfish    93 VNTFRLMLQERQEP-----------------------APPPTEKTAVTETHALAAANQQKNDRL- 133

  Fly   117 RHSSPLLLIISPTTSRREVGDGELDTEEPTGSGGQRKSSVERSLAPVIRGRKSIKDLKEAKEVKS 181
                           |:..|   :.::...||          |..|         |.||.::.|.
Zfish   134 ---------------RQAFG---ISSDYVDGS----------SFNP---------DRKEREKEKR 161

  Fly   182 EEPPAAASESRAASGVTPGQVKEQHVADGNEMESLPITDKKDHKDTKDKGDERETDQ-------- 238
            |:......:.         |.::..:.:.::.:| ....||..|..|.|...||:.:
Zfish   162 EQERLEREKQ---------QQQQYQIIESDDSDS-STEPKKSRKKKKKKNKSRESSESPSPSPHR 216

  Fly   239 ----EEEKEKSADTEIIADTEKTSEKQKYTEKDKAADKDG------------------------- 274
                :::|:|..:..:.:|||.:|..:|.|.|.|....|.
Zfish   217 EKKKDKKKKKKREESVNSDTESSSSDEKETSKGKRKRSDNEAPPPSKSRRRQSASSSPARSQSPQ 281

  Fly   275 -GKEKDIDANKDIDKEKEKVKEVLPP-------------------VVPIAPVTPTCNRVTRKSHA 319
             ||::     |..|...|:|::...|                   ..|....||..|:..:....
Zfish   282 RGKQQ-----KKTDSRPEEVRKGRSPDRRRRGRSQESPKRMEIRERSPRRSRTPEQNKRYKGRER 341

  Fly   320 QEQAINTRVTRNRRQSSTVGANSTASLVAASSSVTEQPPPSRGRRKKPVVVAPPLEPAVKRKRSQ 384
            :.:.:..:..|.|..||:........|.....|...:.||...|........||      .|:.|
Zfish   342 EREQLQEKPQRKRNDSSSRSPPPKQQLDRRPRSEEREKPPQTRRHDSSSPSPPP------NKQRQ 400

  Fly   385 DVEADSDANNSTKYSKVEVVKSEEAEAPEEDSSAVPIKQE---SVDG--NEV------SSISPTV 438
            |....|:          |.:|:...:.|:....:...||:   ..||  |:|      ||.|.|.
Zfish   401 DRRQRSE----------ERLKAPLRKRPDSSPRSPSPKQQRDRRDDGKKNKVQSRHDSSSSSSTS 455

  Fly   439 TPTPTPAP-------------TPAPVPGSR---------------------RGR----GRPQNRN 465
            :|:|:|:|             ..||.|..|                     |||    .:.|.||
Zfish   456 SPSPSPSPRKDRMRRGHSGEKARAPSPRDREKERARGGERISDRDKSRKEDRGRDGDKAKEQARN 520

  Fly   466 SSSPATTTRATRLSKAGSPVI--------LTPVAQEPAPPKRRRV-------------------- 502
            .||.:       :|...||..        |....||....::||.
Zfish   521 RSSDS-------VSPKRSPFANGRQKERELEKERQEQRDREKRREEEMREEALRKARESDREKER 578

  Fly   503 GSSTRKTVSASSLAPSS-------QGGAGDEDSKDSMASS--MDDLLMAAADIKQEKLTPDFDDS 558
            ..|.|:.||.|....||       :|..|.|..::.:...  |::      |.:|||..|
Zfish   579 NRSRREEVSHSDRTSSSRCQPENRRGIRGSEAEQEVLKKDRRMEE------DKRQEKSPP----- 632

  Fly   559 LMPEGLPSTSGASSANGHSCTEPLTVDTEINVKPADSKVKPKESPVVAVEESPSQSETQSAKVSA 623
                             |...|.|....:...|.....|....|...:...|.|:|::.|:..|:
Zfish   633 -----------------HQKMEKLAQKEKTGQKDKAKAVSSSSSSSSSSSSSNSESDSDSSSSSS 680

  Fly   624 HAGKAPSLSPDMISEGVSAVSVRKFYKKPEFLENNLGIEKDPELGEIVQTVSNNDTETDVEMAVD 688
            .:..:.|.|.....:.         .||.:..:::....|......|.|.::..:.|..|.   :
Zfish   681 SSSSSSSSSSSSSDDD---------KKKKQSSKDSTSASKSVPNAVIAQAIARREKENRVR---N 733

  Fly   689 GEVNQ-------------PSTPKSQ----DKKKEEQEKNQKSGLKAA-----------KKAPAKL 725
            ||.::             |..|:|:    :||:.:.|:.::.|..::           |:.....
Zfish   734 GESDEGRKTYPPIQRQSSPPEPQSKRDDVEKKQRDPERERRPGQSSSSFTVMNDRERGKERYTPT 798

  Fly   726 EPKAEDISEILTDVPVDISTEAVEIIEEAEEDTCSNSSIK--------PGELRLDESNDEPELLL 782
            |..:..:|.     |..:...|.::.|.......|.|..:        |.||..:.|...|.
Zfish   799 ETSSPPLSP-----PQRVLDRAAQVGERYMPSGESQSQSRGRGGERYSPSELEQESSRPSPS--- 855

  Fly   783 EDALIVNGDENET-------PDQPEEK----EDQVEFFHT---------GEYDDFEHEIMVELAK 827
                  .|.:.::       |..|.||    ..||:...:         .:|.|.:..:... .:
Zfish   856 ------RGRDRQSDQRKEAPPLSPREKGRIDAPQVKQAASRPSPKRTPPRQYQDPQRSLSPS-PR 913

  Fly   828 EGV-------------LDASGNALSQQKVELEHPEDVTLHESKNDIEAEESVERKP--------- 870
            .||             .|.|...|.::......|.|.. .|...:.....|..|.|
Zfish   914 RGVRRLSPPRNYSPSRRDRSRERLRERDRFRARPADRD-RERSRERRTRNSRSRSPRRPSPPYRS 977

  Fly   871 LKDPSVAD--------EMEDMNEESYIDIKDQTNQLLVEHLAEEAMEADCGPED---NKENLSTS 924
            .:.||.|.        ..|...|:.....:::..|...|...|........|:|   .:.:.|:|
Zfish   978 RRSPSPARRRRSSRSLSREREREQERRRNRERDRQREQEREKEREQRTRVPPKDLTPPRRSPSSS 1042

  Fly   925 ASSTAADGLDIQLAIK----EDDDEEKPLAVIADEQKPGLLLTNDMKVDEKPNGKQESVCDEHVQ 985
            :||:::.....|..::    .|.|:::                 ..:.:|:...||.....:|..
Zfish  1043 SSSSSSSSPSPQRPMRGVKPTDTDKDR-----------------SREANEQARNKQPERTSKHRS 1090

  Fly   986 LVPNLRQEQEIHLQNLGLLTHQAAEHRRKCLLEAQARQAQMQLQQHHH-HQHKRQGARGGGSATH 1049
              |:..:|..:.|.    |:::....|.|..........:::.|.... |:...:|.......:.
Zfish  1091 --PSSPRESRLSLP----LSYRDVPARSKSPTSTDPPGGRLRRQSPTSVHEPSARGKTAVNGKSE 1149

  Fly  1050 VESSGTLKTVIKLNRSSNGGVSGSGGLPTGTVIHGGCGSSSASSTSSSSVGSATRKSSGTLGSGA 1114
            .||||.     :..|||:...|                |||:||:||||..|:....|......|
Zfish  1150 KESSGK-----QQKRSSSSSSS----------------SSSSSSSSSSSSSSSDSSDSEAEKEKA 1193

  Fly  1115 GAGAGVRRQSLKMTFQKGRARGHGAADRS 1143
            |..|...:.:.|..  ||||....::..|
Zfish  1194 GVKASTNKNAGKTA--KGRASSSSSSSES 1220

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
east	NP_001245484.1	PHA03307	295..>535	CDD:223039	67/342 (20%)
srrm2	NP_001025246.2	cwf21	61..103	CDD:285507	9/44 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR36562
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100