Protein Alignment east and Srrm234

DIOPT Version :10

• Sequence 1: NP_001245484.1
• Gene: east / 46006
• FlyBaseID: FBgn0261954
• Length: 2342
• Species: Drosophila melanogaster
• Sequence 2: NP_001097475.2
• Gene: Srrm234 / 38206
• FlyBaseID: FBgn0035253
• Length: 1655
• Species: Drosophila melanogaster
• Alignment Length: 1376
• Identity: 263/1376 - (19%)
• Similarity: 452/1376 - (32%)
• Gaps: 439/1376 - (31%)

  Fly    13 ADESTAAAAPLDDNAN---ASVEIP----DSSEEPAMGVGEEMSIISKT---------RTSTLSV 61
            |..:.||||..|....   |.|..|    |.....|...|:|...:|||         |.|:.|.
  Fly   401 AAAAAAAAAGKDKETGKRYALVRTPSRERDRDAGDAAANGDERDHVSKTDKKKRKKRARESSASP 465

  Fly    62 EPAKEPTVTAELEGEKELESNPVSKTPRSTPTPTLTPAVTPTASDGVAAKSVRVTRHSSPLLLII 126
            |..|:       :..|:.:....||..||                       |..:||.
  Fly   466 ERKKK-------KKSKKHKKESKSKKKRS-----------------------RKRKHSE------ 494

  Fly   127 SPTTSRREVGDGELDTEEP--------------------------------------TGSGGQRK 153
            |...|.|: .|.|.|:.|.                                      |.|..:::
  Fly   495 SGRDSDRD-SDEEDDSSEEERRESKNVRKKAKKDKKKRDKKLKKKSRARASSSDSERTNSPSRKE 558

  Fly   154 SSVERSLAPVIRGRKSIKD--------------LKEAKEVKSEEPPAAASESR------AASGVT 198
            :..:||     ||.|:.|.              .:|.|:.:|..|..|:.:||      .::...
  Fly   559 NKSDRS-----RGAKASKSDEKAPQQENVMRSRSRERKDTRSSRPLEASIDSRQRKPRERSAATP 618

  Fly   199 PGQVKEQHVADGNEMESLPITDKKDHKDTKDKGDERETDQEEEKEKSADTEIIADTEKTSEKQKY 263
            |.:..|:|.....:.:    ..|:.|: ::|:...||..:..|:::|.:.:...:.:::.|:|:.
  Fly   619 PRKEPERHRERSKDRQ----RSKEKHR-SRDRLRSRERQRSRERQRSRERQRSKERQRSKERQRS 678

  Fly   264 TEKDKAADKDGGKEKDIDANKDIDKEKEKVKEVLPPVVPIAPVTPTCN-----RVTRKSHAQEQA 323
            .|:.::.::...||:....:||..:.|||               |.||     |..|:|.::::.
  Fly   679 IERQRSKERQRSKERQRSRSKDALRCKEK---------------PQCNEKERSRERRRSKSKDRQ 728

  Fly   324 INTRVTR---------NRRQSSTVGANSTASLVAASSSVTEQPPPSRGRRKKPVVVAPPLEPAVK 379
            .:....|         .||..||..:...........|...|....|.|.|       ..:.:.:
  Fly   729 RSKEKHRPKDEQQSVDKRRDRSTDRSKENQRSNERQRSKERQRSKERERSK-------DRQRSRE 786

  Fly   380 RKRSQDVEADSD--------ANNSTKYSKVEVVKSEEAEAPEEDSSAVPIKQESVDGNEVSSISP 436
            |:||::.:...|        .:|..|.||......|:..:.|...|..|::.:....::....|
  Fly   787 RRRSKEGQLSKDRQGLKERQRSNERKRSKERQPSKEKQRSRERQRSREPLQSKDRQRSKERQRS- 850

  Fly   437 TVTPTPTPAPTPAPVPGSRRGRGRPQNRNSSSPATTTRA----TRLSKAGSPVILTPVAQEPAPP 497
            ...|.....||.:|...|.:.|   .:|...||...:|.    |:||:  :....:|.....|||
  Fly   851 RERPAKEARPTRSPRERSSKSR---DDRRHRSPTNASRKQKDDTKLSR--NARFKSPAHSPEAPP 910

  Fly   498 KRRRVGSSTRKTVSASSLAPSSQGGAGDEDSKDSMASSMDDLLMAAADIKQEKLTPDFDDSLMPE 562
            |         |:|...:..|..   |.::...|.:.:.  .:::|....|:::
  Fly   911 K---------KSVPTPAFNPFK---AAEDTVNDILGTK--SVMVALEQTKRQR------------ 949

  Fly   563 GLPSTSGASSANGHSCTEPLTVDTE------------INVKPADSKVKPKESPVVAVEESPSQSE 615
            ...|:|..|.::|.|.|...|...:            ..:|....::.|::...|:|:...|.|.
  Fly   950 AASSSSSDSDSSGSSSTSSRTPSPKPTPRKQKKRSKTPELKEVKKEISPRKESRVSVKREQSNSP 1014

  Fly   616 TQSAKVSAHAGKAPSLSPDMISEGVSAVSVRKFY----KKPEFLENNLGIEKDP---------EL 667
            .:|...|    |....||...|....::|....|    :.||...:.:..:|.|         :.
  Fly  1015 QKSKSKS----KVDESSPKRTSRRSRSISSELRYSPAERHPERYHDIVQDKKRPSKVREAHSTKP 1075

  Fly   668 GEIVQTVSNNDTETDVEMAVDGEVNQPSTPKSQDKKKEEQE----KNQKSG--------LKAAKK 720
            ..:|:..:.:|..:|.|..|||...: ...:|:.:::|:||    :..|||        :|..:|
  Fly  1076 APVVRLRAQSDDGSDAETGVDGAALE-EFQQSRREREEQQELRMLEQLKSGIAAKAKQKIKIMEK 1139

  Fly   721 APAK-----------LEPKAEDISEILTDVPVDISTEAVEIIEEAEEDTCSNSSIKPGELRLDES 774
            .|||           ...|...:||.|      ::.....:|......|.:.::..|..|
  Fly  1140 DPAKEGSEVSGSDQVTATKRNSLSEFL------VANNVTALINTLTTTTVTLTTTPPPPL----- 1193

  Fly   775 NDEPELLLEDALIVNGDENETPDQPEEKEDQVEFFHTGEYDDFEHEIMVE------------LAK 827
                      |::|..::.:  :||::::           .|.|..:.||            :.|
  Fly  1194 ----------AVVVPLEQRQ--EQPQQRD-----------PDRELSVPVEDTVKKRDTSTPPICK 1235

  Fly   828 EGVLDASGNALSQQKVELEH------PEDVTLHESKNDIEAEESVERKPLKDPSVADEMEDMNEE 886
            ...:.|:|:|.|...|...|      |.....|.|:.....:....::...:.::     :.|..
  Fly  1236 TPQVTANGDAKSPTLVHKNHVHHNRPPPQHMHHHSQQQQHHQHPPGKRIFHNRTL-----NNNPN 1295

  Fly   887 SYIDIKDQTNQLLVEHLAEEAMEADCG----PEDNKENLSTSASSTAADGLDIQLAIKEDDDEEK 947
            |    :..||.   .|.        ||    |..|..:.::..::..|..|.....
  Fly  1296 S----RHSTNN---PHA--------CGGGGVPHSNSNSSNSGGNNNNAAMLPFLAG--------- 1336

  Fly   948 PLAVIADEQKPGLLLTNDMKVDEKP--NGKQESVCDEHVQLVPNLRQEQEIHL------------ 998
                     .||.......:::..|  .....::|..|..   :|:|:|..||
  Fly  1337 ---------TPGTYNRTTNRLNHGPLLTATHYNICKNHQH---SLQQQQAHHLARGLVYNSALFG 1389

  Fly   999 ---QNLGLLTHQAA---------------EHRR--------KCLLEAQARQAQMQLQQHHHHQHK 1037
               ::.|||:...|               .|.|        .....|.|..|......||||||:
  Fly  1390 HGQRHPGLLSLTGAGVGMSGPGAPLLGHPSHVRGGGGPISFNAAAAAAAVAANSISYLHHHHQHQ 1454

  Fly  1038 RQ-----------------GARGGGSATHV----ESSGTLKTVIKLNRSSNGGVSGSGGLPTGTV 1081
            ::                 .|....|....    .|:.|:.......|.|......|......:.
  Fly  1455 QKPKIVIKPFKIHDPQPLVAALADSSLVDAIVSKVSTATVAAAESAARRSRSRERRSRSKRRTST 1519

  Fly  1082 IHGGCGSSSAS----STSSSSVGS--------------ATRKSSGTLGSGAGAG---AGVRRQSL 1125
            .|....|||.|    |:|||..||              :|..|||:..||:|:|   :|.|..|:
  Fly  1520 SHHRHDSSSESRSRYSSSSSRSGSHSSRSGSHSSRTSCSTNSSSGSSSSGSGSGSSQSGSRSPSI 1584

  Fly  1126 KMTFQKGRARG 1136
            .      |.||
  Fly  1585 P------RRRG 1589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
east	NP_001245484.1	None
Srrm234	NP_001097475.2	cwf21_SRRM2-like	52..100	CDD:410600
		PTZ00121	<560..1154	CDD:173412	131/662 (20%)
		U2AF_lg	747..>876	CDD:273727	27/139 (19%)
		SRRM_C	<1584..1612	CDD:464573	3/12 (25%)