Protein Alignment scw and INHBE

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_113667.1
• Gene: INHBE / 83729
• HGNCID: 24029
• Length: 350
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 78/330 - (23%)
• Similarity: 128/330 - (38%)
• Gaps: 79/330 - (23%)

  Fly   121 KPEQLDNELDMHITF--NTNDVPVDLSLVQAMLRIYKQP-SLVDRRANFTVSVYRKLDNRQDFSY 182
            |.:.||.   :|:|.  .....|...:|.:|:.|:  || |:........:|.....|:...:|.
Human    48 KQQILDG---LHLTSRPRITHPPPQAALTRALRRL--QPGSVAPGNGEEVISFATVTDSTSAYSS 107

  Fly   183 RILGSVNTTSSQ-----RGWLEF--NLTDTLRYWLHNKGLQRRN--------ELRI-SIGDSQLS 231
            .:...::|..|.     |.||..  .|..||...:...|.:||.        |..| ::|...|:
Human   108 LLTFHLSTPRSHHLYHARLWLHVLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLT 172

  Fly   232 TFAAGL----------------------VTPQASRT-----SLEPFIVGYFNGPELLVKIQKLRF 269
            ..::||                      ||.|..|.     ..:||:       ||.::..:...
Human   173 LPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFL-------ELKIRANEPGA 230

  Fly   270 KRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCN 334
            .|  .:||    :|...|..|:        |.|.:..|||:||...:|::.|:.::..:|.|.|.
Human   231 GR--ARRR----TPTCEPATPL--------CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCP 281

  Fly   335 FPLGTK--MNATNHAIVQTLMHLKQP-HLPKPCCVPTVLGAITILRYL--NEDIIDLTKYQKAVA 394
            ..|...  :.|:.|:.|.:|:....| .....|||||....:::| ||  |.:::. |.....|.
Human   282 PHLAGSPGIAASFHSAVFSLLKANNPWPASTSCCVPTARRPLSLL-YLDHNGNVVK-TDVPDMVV 344

  Fly   395 KECGC 399
            :.|||
Human   345 EACGC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	38/178 (21%)
		TGFB	300..400	CDD:214556	32/105 (30%)
INHBE	NP_113667.1	TGF_beta	247..349	CDD:306518	30/103 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810