Protein Alignment scw and Tgfb2

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_112393.2
• Gene: Tgfb2 / 81809
• RGDID: 70491
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 459
• Identity: 103/459 - (22%)
• Similarity: 176/459 - (38%)
• Gaps: 82/459 - (17%)

  Fly     1 MLNVFFLTSLFYAASATTYVTTNNHIEMPIY-QKRPLSEQMEMIDILDLGDRPRRQAEP------ 58
            :|..|.|..|...|.:   ::|.:.::|..: :||..:.:.:::..|.|...|....||
  Rat     5 VLRTFLLLHLVPVALS---LSTCSTLDMDQFMRKRIEAIRGQILSKLKLTSPPEDYPEPDEVPPE 66

  Fly    59 --NLHNSASKFLLEVYNE---ISEDQEPKEVLHQRHKRSLDDDILISNEDRQEI--ASCNSILTF 116
              :::||....|.|..:.   ..|.:...|..:.:....:|......:|....:  .|..|:.:|
  Rat    67 VISIYNSTRDLLQEKASRRAAACERERSDEEYYAKEVYKIDMPSHFPSETVCPVVTTSSGSVGSF 131

  Fly   117 SSRLKPEQLDNELD-----------MHITFNTNDVPVDLS-LVQAMLRIYKQPSLVDRRANFTVS 169
            .|| :.:.|...||           ..:.|:.:.:..:.| ||:|..|:::..:...|.|...:.
  Rat   132 CSR-QSQVLCGYLDAIPPTFYRPYFRIVRFDVSTMEKNASNLVKAEFRVFRLQNPKARVAEQRIE 195

  Fly   170 VYRKLDNRQDFS--YRILGS-VNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLS 231
            :|:.|.::...|  .|.:.| |..|.::..||.|::||.:..|||:|  .|....:||: .....
  Rat   196 LYQILKSKDLTSPTQRYIDSKVVKTRAEGEWLSFDVTDAVHEWLHHK--DRNLGFKISL-HCPCC 257

  Fly   232 TF--AAGLVTPQASRTSLEPFIVG------YFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPP 288
            ||  :...:.|..|: .||....|      |.:|.:..:|          ..|:...|..|....
  Rat   258 TFIPSNNYIIPNKSQ-ELEARFAGIDGTSTYASGDQKTIK----------STRKKSSGKTPHLLL 311

  Fly   289 PPVDLYR--PPQSCERLN--------------------FTVDFKELHMHNWVIAPKKFEAYFCGG 331
            ..:..||  ..||..|..                    ..:|||......|:..||.:.|.||.|
  Rat   312 MLLPSYRLESQQSSRRRKRALDAAYCFRNVQDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAG 376

  Fly   332 GCNFPLGTKMNATNHAIVQTLMHLKQPHL-PKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAK 395
            .|.:...:.   |.|..|.:|.:...|.. ..||||...|..:|||.|:. :...:.:....:.|
  Rat   377 ACPYLWSSD---TQHTKVLSLYNTINPEASASPCCVSQDLEPLTILYYIG-NTPKIEQLSNMIVK 437

  Fly   396 ECGC 399
            .|.|
  Rat   438 SCKC 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	55/250 (22%)
		TGFB	300..400	CDD:214556	29/121 (24%)
Tgfb2	NP_112393.2	TGFb_propeptide	21..256	CDD:395559	52/238 (22%)
		TGF_beta_TGFB2	345..441	CDD:381655	27/99 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810