Protein Alignment scw and BMP8B

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_011540326.2
• Gene: BMP8B / 656
• HGNCID: 1075
• Length: 427
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 117/432 - (27%)
• Similarity: 188/432 - (43%)
• Gaps: 119/432 - (27%)

  Fly    39 QMEMIDILDLGDRPRRQAEP---NLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILIS 100
            |.|::.:|.|..|||.:|.|   .|..||..|:|::|                |..:.|||
Human    45 QREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLY----------------HAMAGDDD---- 89

  Fly   101 NED----RQEIASCNSILTFSSRLKPEQLDNELDMH---ITFNTNDVPVDLSLVQAMLRIYKQPS 158
             ||    .:.:...:.:::|.:.::.::.....:.|   ..|:...:|...::..|..||||.||
Human    90 -EDGAPAERRLGRADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTAAEFRIYKVPS 153

  Fly   159 --LVDRRANFTV-SVYRKLDNRQ-DFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRN 219
              |::|..:.:: .|.::..||: |..:..|.::.  :...|||..::|.....||    |:|..
Human   154 IHLLNRTLHVSMFQVVQEQSNRESDLFFLDLQTLR--AGDEGWLVLDVTAASDCWL----LKRHK 212

  Fly   220 ELRISI----------------GDSQLSTFAAGLVTPQASRTSLEPFIVG-YFNGP-------EL 260
            :|.:.:                .||:|..:...|     |||   |:::. :..||       .|
Human   213 DLGLRLYVETEDGETWTGWGWTKDSRLQMWKLRL-----SRT---PWVLSLHAPGPAQAPAERPL 269

  Fly   261 LVKIQKLRFKRDLEKRRAGGGSPPPPPP-------PPVDLYRPPQS------------------- 299
            |..:|              |..|..|.|       .|:...:|.:|
Human   270 LCLLQ--------------GHCPASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDVHGS 320

  Fly   300 -----CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPH 359
                 |.|....|.|::|...:|||||:.:.||:|.|.|:|||.:.||||||||:|:|:||..|.
Human   321 HGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLMMPD 385

  Fly   360 -LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400
             :||.||.||.|.|.::|.|.:.:.:.|.|::..|.|.||||
Human   386 AVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	56/245 (23%)
		TGFB	300..400	CDD:214556	47/100 (47%)
BMP8B	XP_011540326.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880