DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scw and Inhbc

DIOPT Version :9

Sequence 1:	NP_001286088.1	Gene:	scw / 46000	FlyBaseID:	FBgn0005590	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	NP_072136.1	Gene:	Inhbc / 64549	RGDID:	621194	Length:	351	Species:	Rattus norvegicus

Alignment Length:	376	Identity:	78/376 - (20%)
Similarity:	128/376 - (34%)	Gaps:	102/376 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 FLLEVYNEISEDQEPKEVLHQRH----------------------KRSLDDDILISNEDRQEIAS 109
            |.||.:.|:..|...|.:|.:.|                      .|....:.|:.::.|||.
  Rat    34 FDLESHRELLLDLAKKSILDKLHLSQRPILSRPVSREALKTALRRLRGTRAETLLEHDQRQEY-- 96

  Fly   110 CNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQ-PSLVDRRANFTVSVYRK 173
              .|::|:...........|:.|.:..|..   .:.::|.....:.| |....:..|..|.|.|.
  Rat    97 --EIISFADTGLSNINQTRLEFHFSDRTTG---GVEVLQTRFMFFMQLPPNTTQTMNIRVLVLRP 156

  Fly   174 LDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLV 238
            .|.                        |||.|.:|.|.   :......::.:|....:..:.|.:
  Rat   157 YDT------------------------NLTLTSQYMLQ---VDASGWYQLLLGPEAQAACSQGHL 194

  Fly   239 T------PQASRTSL-------EPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPP 290
            |      .|.:.:||       .||:..            ::|.:.....||.|
  Rat   195 TLELVPESQLAHSSLILDGVSHRPFVAA------------QVRVEGKHRVRRRG----------- 236

  Fly   291 VDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTK----MNATNHAIVQT 351
            ::.....:.|.|..|.|||:|:..|:|:|.|:.:...||.|.|  ||...    ::|:.|..|..
  Rat   237 INCQGLSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCTGQC--PLHVAGMPGISASFHTAVLN 299

  Fly   352 LMHLKQ---PHLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            |:....   ......|||||....:::|.|..:..|..|.....|.:.|||
  Rat   300 LLKANTDAGTARRGSCCVPTSRRPLSLLYYDRDSNIVKTDIPDMVVEACGC 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	40/222 (18%)
scw	NP_001286088.1	TGFB	300..400	CDD:214556	34/107 (32%)
Inhbc	NP_072136.1	TGF_beta_INHBC_E	246..351	CDD:381676	34/107 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810