Protein Alignment scw and bmp7.2

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_017947617.1
• Gene: bmp7.2 / 619363
• XenbaseID: XB-GENE-855954
• Length: 436
• Species: Xenopus tropicalis
• Alignment Length: 431
• Identity: 128/431 - (29%)
• Similarity: 215/431 - (49%)
• Gaps: 56/431 - (12%)

  Fly     7 LTSLFY----AASATTYVTTNNHI-----EMPIYQKRPLSEQMEMIDILDLGDRPRRQAEPNLHN 62
            |..|||    :.|:.|.:..:.|.     .:..:::|.:  |.|::.||.|..|||... |....
 Frog    25 LLFLFYISLSSISSNTILENDFHSSFVQRRLKGHERREI--QKEILTILGLQHRPRPYL-PEKKK 86

  Fly    63 SASKFLLEVYNEIS-EDQEPKEVLHQRHKRSLDD-DILISNEDRQEIASCNSILTFSSRLKPEQL 125
            ||..|::::||.:: ||...::|.:.....||:: ..|.::::...:|..:::::|::.:   :.
 Frog    87 SAPLFMMDLYNAVNIEDLNAEDVSYFNKPVSLNEHSSLATDQENDFLAHADTVMSFANLV---EN 148

  Fly   126 DNEL---DMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQD---FSYRI 184
            ||||   .....|:..|:|:...|..|..||||  ..|:....:.|:||:.|..:.|   :.:::
 Frog   149 DNELYKNRQKFKFDLTDIPLGDELTAAEFRIYK--DYVENNETYQVTVYQVLQKQYDKEPYLFQV 211

  Fly   185 LGSVNTTSSQRGWLEFNLTDTLRYWL----HNKGLQRRNELRI------SIGDSQLSTFAAGLVT 239
             .|.....:::|||.|::|.|..:|:    :|.|||    |.|      |:....:..|  |...
 Frog   212 -DSRTIWGTEKGWLTFDITATSNHWVINPHYNLGLQ----LSIESMDMQSVNPRHVGLF--GRNG 269

  Fly   240 PQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPP--PPPPPVDLYRP------ 296
            ||    ..:||:|.:|...|:.::..:....:...:.||.......  ||....|...|
 Frog   270 PQ----DKQPFMVAFFKTSEIHLRSIRSTSNKHWNQERAKTYKEQDNFPPANISDGIMPTAKRRF 330

  Fly   297 -PQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPH- 359
             .|:|::....|.|::|...:|:|||:.:.||:|.|.|.|||.:.||||||||||||:|...|.
 Frog   331 FKQACKKHELFVSFRDLGWQDWIIAPEGYAAYYCDGECAFPLNSFMNATNHAIVQTLVHFVNPET 395

  Fly   360 LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400
            :|||||.||.|..|::|.:.:...:.|.||:..|.:.||||
 Frog   396 VPKPCCAPTQLNGISVLYFDDSSNVILKKYKNMVVQACGCH 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	63/232 (27%)
		TGF_beta_BMP5_like	299..400	CDD:381639	46/101 (46%)
bmp7.2	XP_017947617.1	TGFb_propeptide	44..280	CDD:459906	65/254 (26%)
		TGF_beta_BMP7	330..436	CDD:381667	47/105 (45%)