Protein Alignment scw and tgfb1b

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_692338.3
• Gene: tgfb1b / 563884
• ZFINID: ZDB-GENE-091028-1
• Length: 379
• Species: Danio rerio
• Alignment Length: 409
• Identity: 89/409 - (21%)
• Similarity: 168/409 - (41%)
• Gaps: 82/409 - (20%)

  Fly    20 VTTNNHIEMP-IYQKRPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYN---EISEDQE 80
            ::|.|.:::. |.:||..:.:.:::..|.|...|..:.:..:.|..:: |:.|||   |::|:|.
Zfish    23 LSTCNPLDLELIKRKRIEAIRGQILSKLRLPKEPEVEEKELIENIPAE-LISVYNSTMELNEEQA 86

  Fly    81 PKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFS-SRLKPEQLDNELDMHITFNTNDVPVDL 144
            ...|.|     :::|       ..:|......|..|: ...|||:       ::.||..|:...|
Zfish    87 ANPVQH-----TIED-------PTEEEYYAKEIHKFTMMEEKPEK-------YLVFNITDIKHKL 132

  Fly   145 S----LVQAMLRI-YKQPSLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTD 204
            .    |.||..|: .|:|.:.|....  :.:|:...|:..:......|:.|...   |:.|::|.
Zfish   133 GANHVLYQAEFRLRIKEPKMGDSEQR--LELYQVTGNKSRYLNSRFISLQTAGK---WVSFDVTS 192

  Fly   205 TLRYWLHNKGLQRRNELRISIG---DSQLSTFA------------AGLVTPQASRTSLEPFIVGY 254
            ||:.||.....::..:|:::..   :||.:.|.            .||:..|.::    |:|: .
Zfish   193 TLKDWLQMPEEKQEFQLQLACSCKPESQNTEFLFKIAGLSRNRGDTGLLADQVAK----PYIL-V 252

  Fly   255 FNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVI 319
            .:.|.......|.|.||:.:               .|...:....|.| :..:||::.....|:.
Zfish   253 MSHPADGHSPAKSRRKRETD---------------AVCTEKSEGCCVR-SLYIDFRKDLGWKWIH 301

  Fly   320 APKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLP----KPCCVPTVLGAITILRYLN 380
            .|..:.|.:|.|.|:: :.|..|..:..:.     |.:.|.|    :|||||.||..:.|:.|:.
Zfish   302 EPSGYYANYCTGSCSY-VWTSENKYSQVLA-----LYRHHNPGASAQPCCVPQVLDPLPIIYYVG 360

  Fly   381 EDIIDLTKYQKAVAKECGC 399
            .. ..:.:....:.|.|.|
Zfish   361 RQ-HKVEQLSNMIVKTCKC 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	51/238 (21%)
		TGF_beta_BMP5_like	299..400	CDD:381639	27/105 (26%)
tgfb1b	XP_692338.3	TGFb_propeptide	23..253	CDD:480997	56/259 (22%)
		TGF_beta_TGFB1	282..378	CDD:381654	26/103 (25%)