Protein Alignment scw and gdf2

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_001165057.2
• Gene: gdf2 / 563287
• ZFINID: ZDB-GENE-100107-1
• Length: 389
• Species: Danio rerio
• Alignment Length: 392
• Identity: 88/392 - (22%)
• Similarity: 164/392 - (41%)
• Gaps: 105/392 - (26%)

  Fly    46 LDLGDRPR--RQAEPNLHNSASKFLLEVYNEISEDQEP------------KEVLHQRHKRSLDDD 96
            |:|...|:  |:.:|      .:|::|:||..:.|:..            ::|::...:.:....
Zfish    64 LNLSGVPQEHRKVQP------PQFMIELYNRYASDKNSIPRSDVIRSFVVQDVIYSIRQGNKTQH 122

  Fly    97 ILISN---EDRQEIASCN-SILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQP 157
            .|:.|   .:.:||.|.. .:.|...|.|| ..|   |:..:.|..||.            |:|
Zfish   123 RLLFNVSIPNHEEITSVQLRLFTLWHRHKP-ACD---DLFTSINVYDVE------------YEQ- 170

  Fly   158 SLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELR 222
                     ...:...||.|.     :..|:||      |..|::|..:|.|  ::..:...|::
Zfish   171 ---------NAKILHLLDGRD-----VRESINT------WEAFDVTGAVRIW--HESRRGAGEIQ 213

  Fly   223 ISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLV---------KIQKLRFKRDL---EK 275
            :.:..| ..:|...|        |||.      |...:::         |.:.:|..:::   |:
Zfish   214 VEVQHS-CDSFDISL--------SLED------NSSAVVIVFSDDLGNRKEESMRKVKEMLVREQ 263

  Fly   276 RRAGGGSPPPPPPPPVDLYRPPQS------CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCN 334
            ::.|..:|..      :.:|..:.      |.|.:..|:||::....|::||.:::||.|.|.|.
Zfish   264 QQVGNQAPVS------NRHRRRKRKAKNNYCRRTSLKVNFKDIGWDKWIVAPPEYDAYECKGVCY 322

  Fly   335 FPLGTKMNATNHAIVQTLMHLKQPHLPK-PCCVPTVLGAITILRYLNEDIIDLTK-YQKAVAKEC 397
            |||...::.:.||::|||::|..|.... .|||||.|..|.:: |..:.:|.:.. |::....:|
Zfish   323 FPLTDDVSPSRHAVIQTLVNLSNPKKANMACCVPTKLDPIAVM-YQEKGVITVRHLYEEMKVAKC 386

  Fly   398 GC 399
            ||
Zfish   387 GC 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	45/225 (20%)
		TGFB	300..400	CDD:214556	36/102 (35%)
gdf2	NP_001165057.2	TGFb_propeptide	60..222	CDD:279078	40/203 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..284		3/26 (12%)
		TGF_beta	288..388	CDD:278448	34/100 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810