DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scw and gdf10a

DIOPT Version :9

Sequence 1:	NP_001286088.1	Gene:	scw / 46000	FlyBaseID:	FBgn0005590	Length:	400	Species:	Drosophila melanogaster
Sequence 2:	XP_691459.3	Gene:	gdf10a / 563003	ZFINID:	ZDB-GENE-090312-17	Length:	441	Species:	Danio rerio

Alignment Length:	140	Identity:	41/140 - (29%)
Similarity:	71/140 - (50%)	Gaps:	16/140 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   263 KIQKLRF-KRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEA 326
            |.|.||| ::.::|.|.             ..::.|:||.|....|||.::..:.|:::||.|:|
Zfish   314 KSQVLRFDEKTMKKARR-------------RQWKEPRSCSRRYLKVDFADIGWNEWILSPKSFDA 365

  Fly   327 YFCGGGCNFPLGTKMNATNHAIVQTLMHLKQ--PHLPKPCCVPTVLGAITILRYLNEDIIDLTKY 389
            ::|.|.|.||:...:..:|||.:|:::....  |.:|:|||||..:..:::|.......|.|..|
Zfish   366 FYCAGTCEFPIPKVVRPSNHATIQSIVKAVGIIPGIPEPCCVPEKMKPLSVLFVDESKNIVLKIY 430

  Fly   390 QKAVAKECGC 399
            .....:.|.|
Zfish   431 PNMSVETCAC 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078
scw	NP_001286088.1	TGFB	300..400	CDD:214556	32/102 (31%)
gdf10a	XP_691459.3	TGF_beta	337..440	CDD:278448	32/102 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810