Protein Alignment scw and gdf9

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_001012383.1
• Gene: gdf9 / 497643
• ZFINID: ZDB-GENE-050221-7
• Length: 418
• Species: Danio rerio
• Alignment Length: 367
• Identity: 75/367 - (20%)
• Similarity: 134/367 - (36%)
• Gaps: 126/367 - (34%)

  Fly    61 HNSASKFLLEVYNEISEDQEPKE--------VLH-------QRHKRSLDDDILISNEDRQEIASC 110
            ||..|.|.|..|.::.|.:..|:        :.|       :.|.|.::.|:
Zfish   149 HNHLSPFSLLCYLDMKEQKSSKDQMCSNHLGIQHSVPLLSFRVHHRWVEVDV------------- 200

  Fly   111 NSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAML-----RIYKQPSLVDRRANFTVSV 170
                  :|.|.|....::.|:|:..|       |:.|:.|:     :|:|.|..:..|   :.|:
Zfish   201 ------TSFLHPLIQAHKKDIHLLIN-------LTCVEDMISRPGGQIHKSPVELTPR---SPSL 249

  Fly   171 YRKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTD-TLRYWLHNKGL------QRRNELRISIGDS 228
            ...|::..:.:|           ||...:..:.| |..:|.....|      :||..|:
Zfish   250 LLYLNDTSEVAY-----------QRRSTQGRMVDLTSNHWDGKSTLWELTSRRRRGTLK------ 297

  Fly   229 QLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDL 293
                         :|.||:...:..|             .|..|
Zfish   298 -------------SSETSMPKLVPMY-------------EFTTD--------------------- 315

  Fly   294 YRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLK-Q 357
                 .|:..:|.|.||||.:.:|:|.|||:...:|.|.|...:|....:..|.:||.|::.| .
Zfish   316 -----DCDLYDFRVSFKELKLDHWIIEPKKYNPRYCKGSCPRNVGFMYGSPMHTMVQNLIYEKLD 375

  Fly   358 PHLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ..:|:|.|||:....:::|.:.|:......:|::.:|.:|.|
Zfish   376 SSVPRPTCVPSEYNPLSVLTFENDKSYAYKEYEEMIATKCAC 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	40/219 (18%)
		TGF_beta_BMP5_like	299..400	CDD:381639	32/102 (31%)
gdf9	NP_001012383.1	TGF_beta_SF	313..418	CDD:477357	33/131 (25%)