DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scw and amh

DIOPT Version :9

Sequence 1:NP_001286088.1 Gene:scw / 46000 FlyBaseID:FBgn0005590 Length:400 Species:Drosophila melanogaster
Sequence 2:NP_001007780.1 Gene:amh / 493624 ZFINID:ZDB-GENE-050706-192 Length:549 Species:Danio rerio


Alignment Length:372 Identity:74/372 - (19%)
Similarity:125/372 - (33%) Gaps:106/372 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    92 SLDDDILISNEDRQEIASCNSILT-----FSSRLKPEQLD-NELD-MHITFNTNDVPVD------ 143
            |:||     |..:..::..|.:|.     .|:.:||..|. ::|| .|:  ..:.:|.|      
Zfish   219 SMDD-----NRRKLSVSELNEVLMRKVDGSSTTIKPVLLFLSDLDEPHL--KRHRIPQDERLPSR 276

  Fly   144 ----LSLVQAMLR-IYKQ---------PSLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTTSSQ 194
                |..:|..|| |..|         ||.|            .||.........||..:|.|..
Zfish   277 TYLFLCELQKFLRDILPQSKSTTPQDDPSAV------------SLDTLHSLPPLRLGVSSTESLL 329

  Fly   195 RGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPE 259
            .|.:..:......:....:||| .:.:.:::....||.....|....|.....|.       |.:
Zfish   330 SGLVNSSTPTVFVFPQRQQGLQ-THRVEVTLDSPLLSVLRMRLDEAMAQVKQQEA-------GRK 386

  Fly   260 LLVKIQKL-----------------------RFKRDL------------EKRRAGGGSPPPPPPP 289
            ::.::|||                       :::..|            |..||...:......|
Zfish   387 MIDRLQKLTELSALSPDGEDSEAATKDHKEAQYRSVLLLKALQMVLSNWESERAQRAARADEDGP 451

  Fly   290 PVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMH 354
            ...     ..|...:.:|..::     :.:.|.:.....|.|.|.|||.   ||.|||::.. .|
Zfish   452 SAS-----NQCHLQSLSVSLRK-----FFLEPSRANINNCEGTCGFPLN---NANNHAVLLN-SH 502

  Fly   355 LK--QPHLPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ::  ||.....||||.....:.::. |..:..:::.....||.:|.|
Zfish   503 IQSGQPVNRSLCCVPVEYDDLCVIE-LESETTNISYKTNVVATKCEC 548

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scwNP_001286088.1 TGFb_propeptide 39..254 CDD:279078 39/188 (21%)
TGFB 300..400 CDD:214556 26/102 (25%)
amhNP_001007780.1 AMH_N 74..439 CDD:282552 45/246 (18%)
TGF_beta 455..548 CDD:278448 25/102 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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