Protein Alignment scw and gdf11

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_998140.1
• Gene: gdf11 / 406247
• ZFINID: ZDB-GENE-040427-2
• Length: 390
• Species: Danio rerio
• Alignment Length: 422
• Identity: 100/422 - (23%)
• Similarity: 151/422 - (35%)
• Gaps: 119/422 - (28%)

  Fly    35 PLSEQMEMI--DILDLGDRPRRQAEPNLHNSASKFL----------------------LEVYNEI 75
            ||||....|  .:.|:.|....:....:....||.|                      .||.|::
Zfish    30 PLSEMSSDIGVSLFDVDDVESSECSACVWREQSKVLRLETIKSQILSKLRLKQAPNISREVVNQL 94

  Fly    76 SEDQEPKEVLHQRH-----KRSLDDDILISNEDRQEI-ASCNSILTFSSRLKPEQLDNELDMHIT 134
            .....|.:.|...|     ..||:|.|     |..|. |:..|::|.:|  :||.| .::|...|
Zfish    95 LPKAPPLQQLLDHHDFQGDASSLEDFI-----DADEYHATTESVITMAS--EPEPL-VQVDGKPT 151

  Fly   135 ---FNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVY------RKLDNRQDFSYRILGSVNT 190
               |..:...:...:::|.|.:|.||      ...|.:||      :.:..:.....||......
Zfish   152 CCFFKFSPKLMFTKVLKAQLWVYLQP------LKQTSTVYLQILRLKPITEQGSRHIRIRSLKIE 210

  Fly   191 TSSQRG-WLEFNLTDTLRYWLH----NKGL------QRRNELRI-SIGDSQLSTFAAGLVTPQAS 243
            ..||.| |...:....|:.|..    |.|:      :..|:|.: |:|..:
Zfish   211 LDSQAGHWQSIDFKHVLQNWFKQPHTNWGIDINAYDESGNDLAVTSLGPGE-------------- 261

  Fly   244 RTSLEPFIVGYFNGPELLVKIQKL--RFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFT 306
             ..|:||         |.|||.:.  |.:|:|..              ..|.:.....|.|...|
Zfish   262 -EGLQPF---------LEVKILETTKRSRRNLGL--------------DCDEHSTESRCCRYPLT 302

  Fly   307 VDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPK----PCCVP 367
            ||| |....:|:||||:::|.:|.|.|.:....|...|         ||.|...|:    |||.|
Zfish   303 VDF-EAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHT---------HLVQHANPRGSAGPCCTP 357

  Fly   368 TVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            |.:..|.:|.:.::..|...|....|...|||
Zfish   358 TKMSPINMLYFNDKQQIIHGKIPGMVVDRCGC 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	53/265 (20%)
		TGFB	300..400	CDD:214556	35/104 (34%)
gdf11	NP_998140.1	TGFb_propeptide	52..268	CDD:279078	50/253 (20%)
		TGFB	296..390	CDD:214556	35/104 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810