Protein Alignment scw and BMP8A

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_861525.2
• Gene: BMP8A / 353500
• HGNCID: 21650
• Length: 402
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 121/390 - (31%)
• Similarity: 193/390 - (49%)
• Gaps: 60/390 - (15%)

  Fly    39 QMEMIDILDLGDRPRRQAEP---NLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILIS 100
            |.|::.:|.|..|||.:|.|   .|..||..|:|::|                |..:.|||
Human    45 QREILAVLGLPGRPRPRAPPAASRLPASAPLFMLDLY----------------HAMAGDDD---- 89

  Fly   101 NED----RQEIASCNSILTFSSRLKPEQLDNELDMH---ITFNTNDVPVDLSLVQAMLRIYKQPS 158
             ||    .|.:...:.:::|.:.::.::.....:.|   ..|:...:|...::..|..||||.||
Human    90 -EDGAPAEQRLGRADLVMSFVNMVERDRALGHQEPHWKEFRFDLTQIPAGEAVTAAEFRIYKVPS 153

  Fly   159 --LVDRRANFTV-SVYRKLDNRQ-DFSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRN 219
              |::|..:.:: .|.::..||: |..:..|.::.  :...|||..::|.....||    |:|..
Human   154 IHLLNRTLHVSMFQVVQEQSNRESDLFFLDLQTLR--AGDEGWLVLDVTAASDCWL----LKRHK 212

  Fly   220 ELRISI------GDSQLSTFAAGLVTPQASRTSLEPFIVGYFN-GPELLVKIQKLRFKRDLEKRR 277
            :|.:.:      |.| :....|||:..:|.| |.:||:|.:|. .|.   .|:..|..|.|.:|:
Human   213 DLGLRLYVETEDGHS-VDPGLAGLLGQRAPR-SQQPFVVTFFRASPS---PIRTPRAVRPLRRRQ 272

  Fly   278 AGGGSPPPPP---PPPVDLYRPP---QSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFP 336
            ....:..|..   |...|..|..   |.|.|....|.|::|...:|||||:.:.||:|.|.|:||
Human   273 PKKSNELPQANRLPGIFDDVRGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFP 337

  Fly   337 LGTKMNATNHAIVQTLMHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400
            |.:.||||||||:|:|:||.:|: :||.||.||.|.|.::|.|.:.:.:.|.|::..|.|.||||
Human   338 LDSCMNATNHAILQSLVHLMKPNAVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGCH 402

  Fly   401  400
            Human   403  402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	60/234 (26%)
		TGFB	300..400	CDD:214556	47/100 (47%)
BMP8A	NP_861525.2	TGFb_propeptide	33..251	CDD:279078	60/234 (26%)
		TGF_beta	299..401	CDD:278448	47/101 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1063560at2759
OrthoFinder	1	1.000	-	-		FOG0000576
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X157
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880