Protein Alignment scw and MSTN

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_005250.1
• Gene: MSTN / 2660
• HGNCID: 4223
• Length: 375
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 93/388 - (23%)
• Similarity: 143/388 - (36%)
• Gaps: 76/388 - (19%)

  Fly    31 YQKRPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDD 95
            :::...|.::|.|.|..| .:.|.:..||:    ||   :|..::.....|...|..::....||
Human    44 WRQNTKSSRIEAIKIQIL-SKLRLETAPNI----SK---DVIRQLLPKAPPLRELIDQYDVQRDD 100

  Fly    96 DILISNEDRQEIASCNSILTFSSRL--------KPEQLDNELDMHITFNTNDVPVDLSLVQAMLR 152
            ....|.||....|:..:|:|..:..        ||:....:....|.:|        .:|:|.|.
Human   101 SSDGSLEDDDYHATTETIITMPTESDFLMQVDGKPKCCFFKFSSKIQYN--------KVVKAQLW 157

  Fly   153 IYKQPSLVDRRANFTVSVYRKLDNRQDFSYRILG----SVNTTSSQRGWLEFNLTDTLRYWLHNK 213
            ||.:|  |:......|.:.|.:...:| ..|..|    .::.......|...::...|:.||.
Human   158 IYLRP--VETPTTVFVQILRLIKPMKD-GTRYTGIRSLKLDMNPGTGIWQSIDVKTVLQNWLK-- 217

  Fly   214 GLQRRNELRISI------GDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRD 272
              |..:.|.|.|      |.....||      |......|.||:       |:.|.....|.:||
Human   218 --QPESNLGIEIKALDENGHDLAVTF------PGPGEDGLNPFL-------EVKVTDTPKRSRRD 267

  Fly   273 LEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPL 337
            ...              ..|.:.....|.|...|||| |....:|:||||:::|.:|.|.|.|..
Human   268 FGL--------------DCDEHSTESRCCRYPLTVDF-EAFGWDWIIAPKRYKANYCSGECEFVF 317

  Fly   338 GTKMNATNHAIVQTLMHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ..|...|:      |:|...|. ...|||.||.:..|.:|.:..::.|...|....|...|||
Human   318 LQKYPHTH------LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGC 374

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	51/232 (22%)
		TGFB	300..400	CDD:214556	35/101 (35%)
MSTN	NP_005250.1	TGFb_propeptide	39..249	CDD:279078	49/233 (21%)
		TGFB	281..375	CDD:214556	35/101 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810