Protein Alignment scw and Bmp6

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_038951315.1
• Gene: Bmp6 / 25644
• RGDID: 2214
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 485
• Identity: 124/485 - (25%)
• Similarity: 199/485 - (41%)
• Gaps: 135/485 - (27%)

  Fly    31 YQKRPLSEQMEMIDILDLGDRP------------------------RRQAEPNLHNSASKFLLEV 71
            ::||.:  |.|::.:|.|..||                        |.:..|....||..|:|::
  Rat    71 HEKREM--QKEILSVLGLPHRPRPLHGLQQPQSPVLPQQQQSQQTAREEPPPGRLKSAPLFMLDL 133

  Fly    72 YNEISEDQEPKEV--------------------------LHQRHKRSL---------------DD 95
            ||.:|:|.|...|                          .|..:::||               .|
  Rat   134 YNSLSKDDEEDGVSEGEGLEPESHGRASSSQLKQPSPGAAHSLNRKSLLAPGPGGSASPLTSAQD 198

  Fly    96 DILISNEDRQEIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLV 160
            ...:::.|.  :.|..:::.:.....|.|..::   ...||.:.:|...::..|..|:||...:.
  Rat   199 SAFLNDADM--VMSFVNLVEYDKEFSPRQRHHK---EFKFNLSQIPEGEAVTAAEFRVYKDCVVG 258

  Fly   161 D-RRANFTVSVYRKLDNRQ--DFSYRILGSVNTTSSQRGWLEFNLTDTLRYWL----HNKGLQRR 218
            . :...|.:|:|:.|...|  |....:|.:....:|:.|||||::|.|...|:    ||.|||
  Rat   259 SFKNQTFLISIYQVLQEHQHRDSDLFLLDTRVVWASEEGWLEFDITATSNLWVVTPQHNMGLQ-- 321

  Fly   219 NELRISIGDS-QLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRR----- 277
              |.:...|. .::..|||||........ :||:|.:|...|:.|:..:....|..::.|
  Rat   322 --LSVVTRDGLHINPRAAGLVGRDGPYDK-QPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQ 383

  Fly   278 ----AGGGSPPPPPPPPVDLYRPPQ---SCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNF 335
                :.|.|...        |...:   :|::....|.|::|...:|:||||.:.|.:|.|.|:|
  Rat   384 SQDVSRGSSASD--------YNSSELKTACKKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSF 440

  Fly   336 PLGTKMNATNHAIVQTL-----------------------------MHLKQP-HLPKPCCVPTVL 370
            ||...||||||||||||                             :||..| ::|||||.||.|
  Rat   441 PLNAHMNATNHAIVQTLVSALTWLVGPGLDPVSFLTVSSHASLLEQVHLMNPEYVPKPCCAPTKL 505

  Fly   371 GAITILRYLNEDIIDLTKYQKAVAKECGCH 400
            .||::|.:.:...:.|.||:..|.:.||||
  Rat   506 NAISVLYFDDNSNVILKKYRNMVVRACGCH 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	64/287 (22%)
		TGF_beta_BMP5_like	299..400	CDD:381639	48/130 (37%)
Bmp6	XP_038951315.1	TGFb_propeptide	58..355	CDD:459906	66/295 (22%)
		TGF_beta_BMP6	404..535	CDD:381666	48/130 (37%)