Protein Alignment scw and Gdf6

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_001013056.1
• Gene: Gdf6 / 252834
• RGDID: 620104
• Length: 452
• Species: Rattus norvegicus
• Alignment Length: 495
• Identity: 122/495 - (24%)
• Similarity: 175/495 - (35%)
• Gaps: 146/495 - (29%)

  Fly     1 MLNVFFLTSLFYAASATTYVTTNNHIEMPIYQKRPL--SEQMEMIDILDLGDR--------PRRQ 55
            :|...||.|..:              ::|.:|:..:  |...|:....|:.:|        |:..
  Rat     7 LLWAIFLISFLW--------------DLPGFQQASISSSSSTELDSTKDVENRKGGKMQRTPQES 57

  Fly    56 AE---PNLHNSASKFLLEVYNEISEDQE-----PKEVLHQ-----RHKRSLDDDILISNEDRQEI 107
            ||   |..|......|.......|..||     |:.|.|:     ....|:.:.:.|:....|..
  Rat    58 AEGRTPKEHRPRPNELRRRLPGQSLGQEPPGRGPRVVPHEYMLSIYRTYSIAEKLGINASFFQSS 122

  Fly   108 ASCNSILTFSSRLKPEQLDNELD--MHITFNTNDVPVDLS-------LVQAMLRIYKQ------- 156
            .|.|:|.:|        :|..||  .|..........|:|       ||.|.||:|:|
  Rat   123 KSANTITSF--------VDRGLDDLSHTPLRRQKYLFDVSTLSDKEELVGAELRLYRQAPPTPWG 179

  Fly   157 ---------------PSLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTL 206
                           |.|:|.|.         ||.:             ..::.||..|::...|
  Rat   180 PQTRPLHLQLFPCLSPLLLDSRT---------LDPQ-------------GPTEAGWEVFDVWQVL 222

  Fly   207 R--YWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGY---FNGPE---LLVK 263
            |  .|     .|...|||...|:.......|....||.| ..|:...:|:   ...|:   |||.
  Rat   223 RPQPW-----KQLCLELRAVWGELDARDSGARPRGPQQS-PPLDLRSLGFGRRVRPPQERALLVV 281

  Fly   264 IQKLRFKR----------DLEKRRAGGGSPPPPPPPPVDLYRPPQS------------------- 299
            ..:.:.|.          ..|...|.|..|.|...|....:.|...
  Rat   282 FTRSQRKNLFTEMHEQLGSAEAAGAEGSWPAPSGAPDAGSWLPSPGRRRRRTALSSRHGKRHGKK 346

  Fly   300 ----CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP-H 359
                |.|....|:||||...:|:|||.::|||.|.|.|:|||.:.:..|||||:||||:...| .
  Rat   347 SRLRCSRKPLHVNFKELGWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMNSMDPGS 411

  Fly   360 LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            .|..|||||.|..|:||.....:.:...:|:..|.:.|||
  Rat   412 TPPSCCVPTKLTPISILYIDAGNNVVYKQYEDMVVESCGC 451

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	57/268 (21%)
		TGFB	300..400	CDD:214556	45/101 (45%)
Gdf6	NP_001013056.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..93		14/63 (22%)
		TGFb_propeptide	66..282	CDD:279078	55/251 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	244..267		6/23 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..348		7/46 (15%)
		TGF_beta	350..451	CDD:278448	43/100 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810