DRSC/TRiP Functional Genomics Resources

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Protein Alignment scw and Gdf15

DIOPT Version :9

Sequence 1:NP_001286088.1 Gene:scw / 46000 FlyBaseID:FBgn0005590 Length:400 Species:Drosophila melanogaster
Sequence 2:NP_001317616.1 Gene:Gdf15 / 23886 MGIID:1346047 Length:303 Species:Mus musculus


Alignment Length:228 Identity:57/228 - (25%)
Similarity:86/228 - (37%) Gaps:37/228 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly   183 RILGSVNTTSSQRGWLE--------FNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVT 239
            ::|..||..|..:|..|        ..||.|.|.|...:.|:|...||             |...
Mouse   101 QLLLRVNRASLSQGLPEAYRVHRALLLLTPTARPWDITRPLKRALSLR-------------GPRA 152

  Fly   240 PQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDL--YRPPQSCER 302
            | |.|..|.|        |..|..:.....:.:|..|.|.|.........|.|.  ..|.:.|..
Mouse   153 P-ALRLRLTP--------PPDLAMLPSGGTQLELRLRVAAGRGRRSAHAHPRDSCPLGPGRCCHL 208

  Fly   303 LNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP-HLPKPCCV 366
            .......::|...:||::|::.:...|.|.|..   ...:|..||.::..:|..|| .:|.||||
Mouse   209 ETVQATLEDLGWSDWVLSPRQLQLSMCVGECPH---LYRSANTHAQIKARLHGLQPDKVPAPCCV 270

  Fly   367 PTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            |:....: :|.:..:..:.|..|...||:.|.|
Mouse   271 PSSYTPV-VLMHRTDSGVSLQTYDDLVARGCHC 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scwNP_001286088.1 TGFb_propeptide 39..254 CDD:279078 21/78 (27%)
TGFB 300..400 CDD:214556 27/101 (27%)
Gdf15NP_001317616.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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