Protein Alignment scw and Tgfb3

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_033394.2
• Gene: Tgfb3 / 21809
• MGIID: 98727
• Length: 412
• Species: Mus musculus
• Alignment Length: 447
• Identity: 103/447 - (23%)
• Similarity: 171/447 - (38%)
• Gaps: 120/447 - (26%)

  Fly    15 SATTYVTTN-NHIEMPIYQKRPLSEQMEMIDILDLGDRPRRQAEPN-----------LHNSASKF 67
            |.:|..|.: .||:    :||..:.:.:::..|.|...|    ||:           |:||..:.
Mouse    23 SLSTCTTLDFGHIK----KKRVEAIRGQILSKLRLTSPP----EPSVMTHVPYQVLALYNSTREL 79

  Fly    68 LLEVYNE-----ISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLKPEQLDN 127
            |.|::.|     ..|..|.:....:.||    .|::....:..|:|.|           |:.:.:
Mouse    80 LEEMHGEREEGCTQETSESEYYAKEIHK----FDMIQGLAEHNELAVC-----------PKGITS 129

  Fly   128 ELDMHITFNTNDVPVD-LSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQD---FSYRILGSV 188
            ::   ..||.:.|..: .:|.:|..|:.:.|:...:|....:.:::.|  |.|   ...|.:|..
Mouse   130 KV---FRFNVSSVEKNGTNLFRAEFRVLRVPNPSSKRTEQRIELFQIL--RPDEHIAKQRYIGGK 189

  Fly   189 N-TTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIG-DSQLSTFAAGLVTPQASRTSLEPFI 251
            | .|.....||.|::|||:|.||    |:|.:.|.:.|. .....||              :|
Mouse   190 NLPTRGTAEWLSFDVTDTVREWL----LRRESNLGLEISIHCPCHTF--------------QP-- 234

  Fly   252 VGYFNGP--ELLVKIQKLRFK----------RDLEKRRAGGGSPPPP------PPPPVDLYRPPQ 298
                ||.  |.:.::.:::||          .||.:.:.......|.      ||..:|  .|.|
Mouse   235 ----NGDILENVHEVMEIKFKGVDNEDDHGRGDLGRLKKQKDHHNPHLILMMIPPHRLD--SPGQ 293

  Fly   299 SCER------LNFT--------------VDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNA 343
            ..:|      .|:.              :||::.....||..||.:.|.||.|.|.:   .:...
Mouse   294 GSQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCPY---LRSAD 355

  Fly   344 TNHAIVQTLMHLKQPHL-PKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            |.|:.|..|.:...|.. ..|||||..|..:|||.|:.. ...:.:....|.|.|.|
Mouse   356 TTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGR-TPKVEQLSNMVVKSCKC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	51/236 (22%)
		TGF_beta_BMP5_like	299..400	CDD:381639	32/122 (26%)
Tgfb3	NP_033394.2	TGFb_propeptide	24..231	CDD:459906	54/238 (23%)
		TGF_beta_TGFB3	312..412	CDD:381656	30/104 (29%)