Protein Alignment scw and Tgfb1

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_035707.1
• Gene: Tgfb1 / 21803
• MGIID: 98725
• Length: 390
• Species: Mus musculus
• Alignment Length: 426
• Identity: 89/426 - (20%)
• Similarity: 162/426 - (38%)
• Gaps: 102/426 - (23%)

  Fly    13 AASATTYVTTNNHIEMPIYQKRPLSE-QMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEI- 75
            ||..:|..|    |:|.:.:::.:.. :.:::..|.|...|.:...|  .....:.:|.:||..
Mouse    27 AAGLSTCKT----IDMELVKRKRIEAIRGQILSKLRLASPPSQGEVP--PGPLPEAVLALYNSTR 85

  Fly    76 ------SEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLKPEQLDNELDMHIT 134
                  |.|.||:.          :.|.......|..:...|:.:...::      |....:::.
Mouse    86 DRVAGESADPEPEP----------EADYYAKEVTRVLMVDRNNAIYEKTK------DISHSIYMF 134

  Fly   135 FNTND----VPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQDFSYRILGS-VNTTSSQ 194
            |||:|    ||....|.:|.||:.:..|.|::.    |.:|:|..|.   |:|.||: :.|.:..
Mouse   135 FNTSDIREAVPEPPLLSRAELRLQRLKSSVEQH----VELYQKYSNN---SWRYLGNRLLTPTDT 192

  Fly   195 RGWLEFNLTDTLRYWLH-NKGLQ------------RRNELRISIGDSQLSTFAAGLVTPQASRTS 246
            ..||.|::|..:|.||: ..|:|            :.|:|.:.|..          ::|: .|..
Mouse   193 PEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNKLHVEING----------ISPK-RRGD 246

  Fly   247 L-------EPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLN 304
            |       .||::......|....:...|.:|.|:.......:              .::|....
Mouse   247 LGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSST--------------EKNCCVRQ 297

  Fly   305 FTVDFKELHMHNWVIAPKKFEAYFCGGGCNF--PLGTKMNATNHAIVQTLMHLKQPHLP----KP 363
            ..:||::.....|:..||.:.|.||.|.|.:  .|.|:.:        .::.|...|.|    .|
Mouse   298 LYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYS--------KVLALYNQHNPGASASP 354

  Fly   364 CCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ||||..|..:.|:.|:... ..:.:....:.:.|.|
Mouse   355 CCVPQALEPLPIVYYVGRK-PKVEQLSNMIVRSCKC 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	53/246 (22%)
		TGFB	300..400	CDD:214556	26/106 (25%)
Tgfb1	NP_035707.1	TGFb_propeptide	30..261	CDD:366248	57/270 (21%)
		Straightjacket domain. /evidence=ECO:0000250|UniProtKB:P07200	30..74		8/49 (16%)
		Arm domain. /evidence=ECO:0000250|UniProtKB:P07200	75..271		50/229 (22%)
		Bowtie tail. /evidence=ECO:0000250|UniProtKB:P01137	226..252		6/36 (17%)
		Cell attachment site. /evidence=ECO:0000255	244..246		1/1 (100%)
		TGF_beta_TGFB1	292..390	CDD:381654	26/107 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810