Protein Alignment scw and Nodal

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_038639.2
• Gene: Nodal / 18119
• MGIID: 97359
• Length: 354
• Species: Mus musculus
• Alignment Length: 302
• Identity: 73/302 - (24%)
• Similarity: 128/302 - (42%)
• Gaps: 61/302 - (20%)

  Fly   134 TFNTNDVPVDLSLVQAMLRI-YKQPSLVDRRANFTVSVYR--KLDNRQD----------FSYRIL 185
            ||:.:.:..:..||.|.||: ...|..:......|:.::.  |.|..:|          .::.::
Mouse    77 TFDFSFLSQEEDLVWAELRLQLPGPMDIPTEGPLTIDIFHQAKGDPERDPADCLERIWMETFTVI 141

  Fly   186 GSVNTTSSQRGWLEFNLTDTLRYWLHN-KGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEP 249
            .|..|.:|....||  :|..|..||.: :.|:::                   |:.:|.:...:|
Mouse   142 PSQVTFASGSTVLE--VTKPLSKWLKDPRALEKQ-------------------VSSRAEKCWHQP 185

  Fly   250 FIVGYFNGPELLVKIQKLRFKRDLEKRRAGGG-------SPPPPPPPPVDLYR------------ 295
            :....   |.....:..|...|..|:|:.||.       |........:.:.|
Mouse   186 YTPPV---PVASTNVLMLYSNRPQEQRQLGGATLLWEAESSWRAQEGQLSVERGGWGRRQRRHHL 247

  Fly   296 PPQS--CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQP 358
            |.:|  |.|:.|.|||..:...:|:|.||::.||.|.|.|..|:|.:.:.||||.:|:|:...||
Mouse   248 PDRSQLCRRVKFQVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQP 312

  Fly   359 H-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            | :|..||.|.....:::| |::...:.|..::..:.:||||
Mouse   313 HRVPSTCCAPVKTKPLSML-YVDNGRVLLEHHKDMIVEECGC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	25/133 (19%)
		TGFB	300..400	CDD:214556	37/101 (37%)
Nodal	NP_038639.2	TGFb_propeptide	33..169	CDD:279078	21/93 (23%)
		TGFB	254..353	CDD:214556	35/99 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810