DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment scw and Mstn

DIOPT Version :9

Sequence 1:NP_001286088.1 Gene:scw / 46000 FlyBaseID:FBgn0005590 Length:400 Species:Drosophila melanogaster
Sequence 2:NP_034964.1 Gene:Mstn / 17700 MGIID:95691 Length:376 Species:Mus musculus


Alignment Length:361 Identity:90/361 - (24%)
Similarity:130/361 - (36%) Gaps:74/361 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    65 SKFLLEVYNEISED--------QEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRL- 120
            ||..||....||:|        ..|...|..::....||....|.||....|:..:|:|..:.. 
Mouse    63 SKLRLETAPNISKDAIRQLLPRAPPLRELIDQYDVQRDDSSDGSLEDDDYHATTETIITMPTESD 127

  Fly   121 -------KPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQ 178
                   ||:....:....|.:|        .:|:|.|.||.:|  |.......|.:.|.:...:
Mouse   128 FLMQADGKPKCCFFKFSSKIQYN--------KVVKAQLWIYLRP--VKTPTTVFVQILRLIKPMK 182

  Fly   179 DFS-YRILGSVNTTSSQRG--WLEFNLTDTLRYWLHNKGLQRRNELRISI------GDSQLSTFA 234
            |.: |..:.|:....|...  |...::...|:.||.    |..:.|.|.|      |.....|| 
Mouse   183 DGTRYTGIRSLKLDMSPGTGIWQSIDVKTVLQNWLK----QPESNLGIEIKALDENGHDLAVTF- 242

  Fly   235 AGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQS 299
                 |......|.||:       |:.|.....|.:||...              ..|.:.....
Mouse   243 -----PGPGEDGLNPFL-------EVKVTDTPKRSRRDFGL--------------DCDEHSTESR 281

  Fly   300 CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPH-LPKP 363
            |.|...|||| |....:|:||||:::|.:|.|.|.|....|...|:      |:|...|. ...|
Mouse   282 CCRYPLTVDF-EAFGWDWIIAPKRYKANYCSGECEFVFLQKYPHTH------LVHQANPRGSAGP 339

  Fly   364 CCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ||.||.:..|.:|.:..::.|...|....|...|||
Mouse   340 CCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGC 375

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scwNP_001286088.1 TGFb_propeptide 39..254 CDD:279078 49/213 (23%)
TGFB 300..400 CDD:214556 35/101 (35%)
MstnNP_034964.1 TGFb_propeptide 37..250 CDD:366248 46/206 (22%)
TGF_beta_GDF8 269..376 CDD:381658 36/128 (28%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

Return to query results.
Submit another query.