Protein Alignment scw and Inhbe

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_032408.2
• Gene: Inhbe / 16326
• MGIID: 109269
• Length: 350
• Species: Mus musculus
• Alignment Length: 323
• Identity: 75/323 - (23%)
• Similarity: 122/323 - (37%)
• Gaps: 82/323 - (25%)

  Fly   131 MHITFN---TNDVPVDLSLVQAMLRIYKQP-SLVDRRANFTVSVYRKLDNRQDFSYRILGSVNTT 191
            :|:|..   |..:| ..:|.:|:.|:  || |:|.......:|....:|             .:|
Mouse    55 LHLTSRPRITRPLP-QAALTRALRRL--QPKSMVPGNREKVISFATIID-------------KST 103

  Fly   192 SSQRGWLEFNLTDT-------LRYWLH--------------NKGLQRRNELRISIGDSQLSTFAA 235
            |:.|..|.|.|:..       .|.|||              ..|..|....|..:.:.|  |.::
Mouse   104 STYRSMLTFQLSPLWSHHLYHARLWLHVPPSFPGTLYLRIFRCGTTRCRGFRTFLAEHQ--TTSS 166

  Fly   236 G---LVTPQASRTSLEPFIVGY--------FNG-----PELLVKI---QKLRFKRDLEKRRAGGG 281
            |   |..|.:...|.:..:|..        .|.     |.||:..   |:...:..:.....|.|
Mouse   167 GWHALTLPSSGLRSEDSGVVKLQLEFRPLDLNSTAAGLPRLLLDTAGQQRPFLELKIRANEPGAG 231

  Fly   282 -----SPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTK- 340
                 :|...|..|:        |.|.:..|||:||...:|::.|:.::..:|.|.|...|...
Mouse   232 RARRRTPTCEPETPL--------CCRRDHYVDFQELGWRDWILQPEGYQLNYCSGQCPPHLAGSP 288

  Fly   341 -MNATNHAIVQTLMHLKQP-HLPKPCCVPTVLGAITILRYL--NEDIIDLTKYQKAVAKECGC 399
             :.|:.|:.|.:|:....| .....|||||....:::| ||  |.:::. |.....|.:.|||
Mouse   289 GIAASFHSAVFSLLKANNPWPAGSSCCVPTARRPLSLL-YLDHNGNVVK-TDVPDMVVEACGC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	33/150 (22%)
		TGF_beta_BMP5_like	299..400	CDD:381639	32/106 (30%)
Inhbe	NP_032408.2	TGF_beta_INHBC_E	247..350	CDD:381676	32/105 (30%)