Protein Alignment scw and Inhba

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_032406.1
• Gene: Inhba / 16323
• MGIID: 96570
• Length: 424
• Species: Mus musculus
• Alignment Length: 422
• Identity: 88/422 - (20%)
• Similarity: 158/422 - (37%)
• Gaps: 116/422 - (27%)

  Fly    50 DRPRRQAEPNLHNSASKFLLEVYN-----EISEDQEPKEVLHQRHKR------------SLDDDI 97
            |.|..|  |.:..:..|.:|.:.:     :::: ..||..|....::            .::|||
Mouse    46 DGPNSQ--PEMVEAVKKHILNMLHLKKRPDVTQ-PVPKAALLNAIRKLHVGKVGENGYVEIEDDI 107

  Fly    98 LISNEDRQEIASCNSILTFSSRLKPEQLDNELDMHITFNTNDVPVDLSLVQ-AMLRIY-KQPSLV 160
            ....|..:.:...:.|:||:     |.......:|  |..:....|||:|: |.:.:: |.|...
Mouse   108 GRRAEMNELMEQTSEIITFA-----ESGTARKTLH--FEISKEGSDLSVVERAEVWLFLKVPKAN 165

  Fly   161 DRRANFTVSVYRKLDNRQDFSYRILGSVNT--TSSQRG---------------------WLEFNL 202
            ..|...|:.::::..:.|       ||::|  .:.:.|                     |..|.:
Mouse   166 RTRTKVTIRLFQQQKHPQ-------GSLDTGDEAEEMGLKGERSELLLSEKVVDARKSTWHIFPV 223

  Fly   203 TDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKL 267
            :.:::..|.    |.::.|.:.|...|.....|.||                     ||.|.:|.
Mouse   224 SSSIQRLLD----QGKSSLDVRIACEQCQESGASLV---------------------LLGKKKKK 263

  Fly   268 RFKRDLEKRRAGGG---SPPPPPPPPVDLYRPPQS--------------------CERLNFTVDF 309
            ....|.:|:....|   ........|..:.:..||                    |.:..|.|.|
Mouse   264 EVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLECDGKVNICCKKQFFVSF 328

  Fly   310 KELHMHNWVIAPKKFEAYFCGGGC-NFPLGTKMNATN-HAIVQTLMHLK-QPHLP----KPCCVP 367
            |::..::|:|||..:.|.:|.|.| :...||..::.: |:.|  :.|.: :.|.|    |.||||
Mouse   329 KDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTV--INHYRMRGHSPFANLKSCCVP 391

  Fly   368 TVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            |.|..:::|.|.:...|.....|..:.:||||
Mouse   392 TKLRPMSMLYYDDGQNIIKKDIQNMIVEECGC 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	43/245 (18%)
		TGF_beta_BMP5_like	299..400	CDD:381639	36/128 (28%)
Inhba	NP_032406.1	TGFb_propeptide	56..291	CDD:480997	47/274 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		6/41 (15%)
		TGF_beta_INHBA	317..424	CDD:381674	35/109 (32%)