Protein Alignment scw and GDF7

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_878248.2
• Gene: GDF7 / 151449
• HGNCID: 4222
• Length: 450
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 69/253 - (27%)
• Similarity: 96/253 - (37%)
• Gaps: 61/253 - (24%)

  Fly   197 WLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSLEPFIVGYFNG---- 257
            |..|::.|.:|        :.|.|.|.......|....||   |..|..:|.....|:..|
Human   208 WEAFDVADAMR--------RHRREPRPPRAFCLLLRAVAG---PVPSPLALRRLGFGWPGGGGSA 261

  Fly   258 ---PELLVKIQKLRFKRDL------EKRRAGGGSPPPPPPPPVDLYRPPQS-------------- 299
               ..:||...:.:.|..|      :.|..|......|.|.|......|::
Human   262 AEERAVLVVSSRTQRKESLFREIRAQARALGAALASEPLPDPGTGTASPRAVIGGRRRRRTALAG 326

  Fly   300 ----------------------CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMN 342
                                  |.|....||||||...:|:|||..:|||.|.|.|:|||.:.:.
Human   327 TRTAQGSGGGAGRGHGRRGRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLE 391

  Fly   343 ATNHAIVQTLMHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            .|||||:|||::...|. .|..||||..|..|:||.....:.:...:|:..|.:.|||
Human   392 PTNHAIIQTLLNSMAPDAAPASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	13/56 (23%)
		TGFB	300..400	CDD:214556	44/101 (44%)
GDF7	NP_878248.2	TGFb_propeptide	<91..>217	CDD:279078	3/8 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	296..349		4/52 (8%)
		TGFB	352..450	CDD:214556	42/98 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810