Protein Alignment scw and Bmp7

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_031583.2
• Gene: Bmp7 / 12162
• MGIID: 103302
• Length: 430
• Species: Mus musculus
• Alignment Length: 439
• Identity: 136/439 - (30%)
• Similarity: 212/439 - (48%)
• Gaps: 77/439 - (17%)

  Fly    10 LFYAASATTYVTTNNHIEMPIYQKRPLSE-----QMEMIDILDLGDRPRRQAEPNL---HNSASK 66
            ||...||....:.:|.:......:|..|:     |.|::.||.|..|||    |:|   ||||..
Mouse    21 LFLLRSALADFSLDNEVHSSFIHRRLRSQERREMQREILSILGLPHRPR----PHLQGKHNSAPM 81

  Fly    67 FLLEVYNEIS-EDQEP---------KEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLK 121
            |:|::||.:: |:..|         |.|.      |.....|.|.:|...:...:.:::|.:.:
Mouse    82 FMLDLYNAMAVEESGPDGQGFSYPYKAVF------STQGPPLASLQDSHFLTDADMVMSFVNLV- 139

  Fly   122 PEQLDNEL------DMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRAN--FTVSVYRKLDNRQ 178
              :.|.|.      .....|:.:.:|...::..|..||||. .:.:|..|  |.::||:.|   |
Mouse   140 --EHDKEFFHPRYHHREFRFDLSKIPEGEAVTAAEFRIYKD-YIRERFDNETFQITVYQVL---Q 198

  Fly   179 DFSYR-----ILGSVNTTSSQRGWLEFNLTDTLRYWL----HNKGLQRRNELRISIGDSQ-LSTF 233
            :.|.|     :|.|....:|:.|||.|::|.|..:|:    ||.|||    |.:...|.| ::..
Mouse   199 EHSGRESDLFLLDSRTIWASEEGWLVFDITATSNHWVVNPRHNLGLQ----LSVETLDGQSINPK 259

  Fly   234 AAGLV---TPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYR 295
            .|||:   .||    :.:||:|.:|...|  |.::.:|....  |:|:...|..|.....:.:..
Mouse   260 LAGLIGRHGPQ----NKQPFMVAFFKATE--VHLRSIRSTGG--KQRSQNRSKTPKNQEALRMAS 316

  Fly   296 --------PPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTL 352
                    ..|:|::....|.|::|...:|:|||:.:.||:|.|.|.|||.:.||||||||||||
Mouse   317 VAENSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTL 381

  Fly   353 MHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGCH 400
            :|...|. :|||||.||.|.||::|.:.:...:.|.||:..|.:.||||
Mouse   382 VHFINPDTVPKPCCAPTQLNAISVLYFDDSSNVILKKYRNMVVRACGCH 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	71/248 (29%)
		TGF_beta_BMP5_like	299..400	CDD:381639	47/101 (47%)
Bmp7	NP_031583.2	TGFb_propeptide	35..279	CDD:459906	74/268 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	290..310		5/21 (24%)
		TGF_beta_BMP7	324..430	CDD:381667	48/105 (46%)