Protein Alignment scw and Bmp4

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_031580.2
• Gene: Bmp4 / 12159
• MGIID: 88180
• Length: 408
• Species: Mus musculus
• Alignment Length: 398
• Identity: 99/398 - (24%)
• Similarity: 163/398 - (40%)
• Gaps: 109/398 - (27%)

  Fly    53 RRQAEPNLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFS 117
            ||:.:|:.......::.::|...|.::|.:|   |.....|:       ...:..:..|::.:|.
Mouse    68 RRRPQPSKSAVIPDYMRDLYRLQSGEEEEEE---QSQGTGLE-------YPERPASRANTVRSFH 122

  Fly   118 SRLKPEQLDN------ELDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANF-----TVSVY 171
            ..   |.|:|      .......||.:.:|.:..:..|.||::::.  ||:..::     .:::|
Mouse   123 HE---EHLENIPGTSESSAFRFLFNLSSIPENEVISSAELRLFREQ--VDQGPDWEQGFHRINIY 182

  Fly   172 ----------------RKLDNRQDFSYRILGSVNTTSSQRGWLEFNLTDTLRYW----------- 209
                            |.||.|       |...|.|.    |..|:::..:..|
Mouse   183 EVMKPPAEMVPGHLITRLLDTR-------LVHHNVTR----WETFDVSPAVLRWTREKQPNYGLA 236

  Fly   210 -----LHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASR--TSLEPFIVGYFNGPELLVKIQKL 267
                 ||.....:...:|||..            .||.|.  ..|.|.:|
Mouse   237 IEVTHLHQTRTHQGQHVRISRS------------LPQGSGDWAQLRPLLV--------------- 274

  Fly   268 RFKRD-----LEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAY 327
            .|..|     |.:|||    ...|...|....:..::|.|.:..|||.::..::|::||..::|:
Mouse   275 TFGHDGRGHTLTRRRA----KRSPKHHPQRSRKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAF 335

  Fly   328 FCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTVLGAITILRYLNE-DIIDLTKYQK 391
            :|.|.|.|||...:|:|||||||||::.....:||.|||||.|.||::| ||:| |.:.|..||:
Mouse   336 YCHGDCPFPLADHLNSTNHAIVQTLVNSVNSSIPKACCVPTELSAISML-YLDEYDKVVLKNYQE 399

  Fly   392 AVAKECGC 399
            .|.:.|||
Mouse   400 MVVEGCGC 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	44/245 (18%)
		TGF_beta_BMP5_like	299..400	CDD:381639	47/102 (46%)
Bmp4	NP_031580.2	TGFb_propeptide	43..276	CDD:459906	44/260 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..111		5/29 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	281..307		6/29 (21%)
		TGF_beta_BMP4_BMP2B	302..408	CDD:381661	47/107 (44%)