DRSC/TRiP Functional Genomics Resources

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Protein Alignment scw and Bmp2

DIOPT Version :9

Sequence 1:NP_001286088.1 Gene:scw / 46000 FlyBaseID:FBgn0005590 Length:400 Species:Drosophila melanogaster
Sequence 2:NP_031579.2 Gene:Bmp2 / 12156 MGIID:88177 Length:394 Species:Mus musculus


Alignment Length:421 Identity:115/421 - (27%)
Similarity:170/421 - (40%) Gaps:121/421 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 RPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISEDQEP---KEV--------LHQ 87
            ||||...|  |:|                  |:|.|.:.:.....|.|   |:|        |::
Mouse    39 RPLSRPSE--DVL------------------SEFELRLLSMFGLKQRPTPSKDVVVPPYMLDLYR 83

  Fly    88 RHKRSLDDDILISNEDRQEIAS--CNSILTFSSRLKPEQL---DNELDMHITFNTNDVPVDLSLV 147
            ||.......   :.:.|.|.|:  .|::.:|......|:|   ..:......||.:.||.|..|.
Mouse    84 RHSGQPGAP---APDHRLERAASRANTVRSFHHEEAVEELPEMSGKTARRFFFNLSSVPSDEFLT 145

  Fly   148 QAMLRIYKQP-------SLVDRR-----------ANFTVSVYRKLDNRQDFSYRILGSVNTTSSQ 194
            .|.|:|:::.       |....|           ||....|.|.||.|         .||..:||
Mouse   146 SAELQIFREQIQEALGNSSFQHRINIYEIIKPAAANLKFPVTRLLDTR---------LVNQNTSQ 201

  Fly   195 RGWLEFNLTDTLRYWL-----------------HNKGLQRRNELRISIGDSQLSTFAAGLVTPQA 242
              |..|::|..:..|.                 .|.|:.:|: :|||          ..|...:.
Mouse   202 --WESFDVTPAVMRWTTQGHTNHGFVVEVAHLEENPGVSKRH-VRIS----------RSLHQDEH 253

  Fly   243 SRTSLEPFIV--GYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNF 305
            |.:.:.|.:|  |:......|.|.:|.:.|....||.                   ..||:|...
Mouse   254 SWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRL-------------------KSSCKRHPL 299

  Fly   306 TVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTVL 370
            .|||.::..::|::||..:.|::|.|.|.|||...:|:|||||||||::.....:||.|||||.|
Mouse   300 YVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL 364

  Fly   371 GAITILRYL--NEDIIDLTKYQKAVAKECGC 399
            .||::| ||  ||.:: |..||..|.:.|||
Mouse   365 SAISML-YLDENEKVV-LKNYQDMVVEGCGC 393

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
scwNP_001286088.1 TGFb_propeptide 39..254 CDD:279078 56/267 (21%)
TGFB 300..400 CDD:214556 47/102 (46%)
Bmp2NP_031579.2 TGFb_propeptide 43..265 CDD:279078 56/266 (21%)
TGFB 294..394 CDD:214556 47/102 (46%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X157
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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