Protein Alignment scw and Bmp2

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_031579.2
• Gene: Bmp2 / 12156
• MGIID: 88177
• Length: 394
• Species: Mus musculus
• Alignment Length: 421
• Identity: 115/421 - (27%)
• Similarity: 170/421 - (40%)
• Gaps: 121/421 - (28%)

  Fly    34 RPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISEDQEP---KEV--------LHQ 87
            ||||...|  |:|                  |:|.|.:.:.....|.|   |:|        |::
Mouse    39 RPLSRPSE--DVL------------------SEFELRLLSMFGLKQRPTPSKDVVVPPYMLDLYR 83

  Fly    88 RHKRSLDDDILISNEDRQEIAS--CNSILTFSSRLKPEQL---DNELDMHITFNTNDVPVDLSLV 147
            ||.......   :.:.|.|.|:  .|::.:|......|:|   ..:......||.:.||.|..|.
Mouse    84 RHSGQPGAP---APDHRLERAASRANTVRSFHHEEAVEELPEMSGKTARRFFFNLSSVPSDEFLT 145

  Fly   148 QAMLRIYKQP-------SLVDRR-----------ANFTVSVYRKLDNRQDFSYRILGSVNTTSSQ 194
            .|.|:|:::.       |....|           ||....|.|.||.|         .||..:||
Mouse   146 SAELQIFREQIQEALGNSSFQHRINIYEIIKPAAANLKFPVTRLLDTR---------LVNQNTSQ 201

  Fly   195 RGWLEFNLTDTLRYWL-----------------HNKGLQRRNELRISIGDSQLSTFAAGLVTPQA 242
              |..|::|..:..|.                 .|.|:.:|: :|||          ..|...:.
Mouse   202 --WESFDVTPAVMRWTTQGHTNHGFVVEVAHLEENPGVSKRH-VRIS----------RSLHQDEH 253

  Fly   243 SRTSLEPFIV--GYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNF 305
            |.:.:.|.:|  |:......|.|.:|.:.|....||.                   ..||:|...
Mouse   254 SWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRL-------------------KSSCKRHPL 299

  Fly   306 TVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTVL 370
            .|||.::..::|::||..:.|::|.|.|.|||...:|:|||||||||::.....:||.|||||.|
Mouse   300 YVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTEL 364

  Fly   371 GAITILRYL--NEDIIDLTKYQKAVAKECGC 399
            .||::| ||  ||.:: |..||..|.:.|||
Mouse   365 SAISML-YLDENEKVV-LKNYQDMVVEGCGC 393

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	56/267 (21%)
		TGF_beta_BMP5_like	299..400	CDD:381639	48/103 (47%)
Bmp2	NP_031579.2	TGFb_propeptide	45..265	CDD:459906	56/264 (21%)
		TGF_beta_BMP2	292..394	CDD:381660	48/104 (46%)