Protein Alignment scw and LEFTY1

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_066277.1
• Gene: LEFTY1 / 10637
• HGNCID: 6552
• Length: 366
• Species: Homo sapiens
• Alignment Length: 296
• Identity: 65/296 - (21%)
• Similarity: 104/296 - (35%)
• Gaps: 85/296 - (28%)

  Fly   140 VPVDLSLVQAMLRIYKQP------------SLVDRRANFTVSVYRKLDNRQDFSYR--ILGSVNT 190
            :|.:..||||:||::::|            |....||..||...|.   |.|.|.|  ::.|...
Human   107 LPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRV---RDDGSNRTSLIDSRLV 168

  Fly   191 TSSQRGWLEFNLTDTLRYW----------LHNKGLQRRNELRISIGDSQLSTFA-----AGLVTP 240
            :..:.||..|::|:.:.:|          |....:||.:...::.|..:|..||     |||..|
Human   169 SVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEP 233

  Fly   241 QASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNF 305
            |....:|                        ||....|.|...|..|      ......|.|...
Human   234 QLELHTL------------------------DLGDYGAQGDCDPEAP------MTEGTRCCRQEM 268

  Fly   306 TVDFKELH-MHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTV 369
            .:|.:.:. ..|||:.|..|.||.|.|.|..|             ...:..|.|.|....|:.:.
Human   269 YIDLQGMKWAENWVLEPPGFLAYECVGTCRQP-------------PEALAFKWPFLGPRQCIASE 320

  Fly   370 LGAITILRYLNE------DIIDLTKYQKAVAKECGC 399
            ..::.::..:.|      .::.|...:   .::|.|
Human   321 TDSLPMIVSIKEGGRTRPQVVSLPNMR---VQKCSC 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	37/142 (26%)
		TGFB	300..400	CDD:214556	22/107 (21%)
LEFTY1	NP_066277.1	TGFb_propeptide	<106..214	CDD:307025	27/109 (25%)
		TGF_beta	263..353	CDD:306518	21/105 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810