Protein Alignment scw and tgfb1

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_002939433.1
• Gene: tgfb1 / 100498430
• XenbaseID: XB-GENE-488111
• Length: 381
• Species: Xenopus tropicalis
• Alignment Length: 434
• Identity: 98/434 - (22%)
• Similarity: 167/434 - (38%)
• Gaps: 94/434 - (21%)

  Fly     1 MLNVFFLTSLFYAASATTYVTTNNHIEMPIYQKRPLSE-QMEMIDILDLGDRPRRQAEP------ 58
            ||.|..:..|   ::.|..::|...::|...:||.:.. :.:::..|.|...|...:|.
 Frog     6 MLPVLLVLHL---STLTMSMSTCKTVDMEEVRKRRIEAIRGQILSKLKLDRTPDVDSENMTVPSE 67

  Fly    59 --NLHNSASKFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLK 121
              :|:||.    |||..|.:..:|..  :.|.|.        |.:...:::....||    :.||
 Frog    68 AISLYNST----LEVIRERAAKEEAP--VWQEHN--------IQDYYAKQVHRFESI----NELK 114

  Fly   122 PEQLDNELDMHITFNTNDVPVDLS----LVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQDFSY 182
                  |.:...|||.:.|..::.    |..|.||:|::.. .|:.....:.:|  ..|..|:|.
 Frog   115 ------ENEFLFTFNASHVRENVGMKSLLHHAELRMYRKKQ-TDKNVEQRMELY--AGNGTDYSG 170

  Fly   183 RILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTFAAGLVTPQASRTSL 247
            .:.....|..:...|:.|::|.|:..||::   ...||      :.:|.......:|..:...|:
 Frog   171 YLDSKFFTAVTDDEWVSFDVTKTVNEWLNH---AEENE------EFRLKPACKCSITTHSKVISI 226

  Fly   248 EPFIVGYFNG------------PELLV---------KIQKLRFKRDLEKRRAGGGSPPPPPPPPV 291
            |.|.:  ..|            |.||:         .:...|.||.:.:....|.|.|.....|
 Frog   227 EGFSI--LRGDLMNLGGDDLKKPYLLITSMPAERIDTVSHSRRKRGVGQEYCFGNSGPNCCVKP- 288

  Fly   292 DLYRPPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLK 356
             ||        :||..|..    ..|:..||.:||.:|.|.|.:...|.   |.::.|.:|.:..
 Frog   289 -LY--------INFRKDLG----WKWIHEPKGYEANYCLGNCPYIWSTD---TQYSKVLSLYNQN 337

  Fly   357 QPHLP-KPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            .|... .|||||.||..:.|:.|:..: ..:.:....|.:.|.|
 Frog   338 NPGASISPCCVPDVLEPLPIIYYVGRN-AKVEQLSNMVVRSCHC 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	48/226 (21%)
		TGFB	300..400	CDD:214556	28/101 (28%)
tgfb1	XP_002939433.1	TGFb_propeptide	22..250	CDD:366248	54/265 (20%)
		TGF_beta_TGFB1	283..381	CDD:381654	31/116 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910