Protein Alignment scw and tgfb2

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_002936067.1
• Gene: tgfb2 / 100489680
• XenbaseID: XB-GENE-480560
• Length: 411
• Species: Xenopus tropicalis
• Alignment Length: 430
• Identity: 103/430 - (23%)
• Similarity: 162/430 - (37%)
• Gaps: 100/430 - (23%)

  Fly    35 PLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISED-QEPKEVLHQRHKRSLDDDIL 98
            |::..:.....||:....|::.|.......||..|   |...|| .||.||        ..|.|.
 Frog    16 PVALSLSTCSTLDMDQFMRKRIEAIRGQILSKLKL---NSPPEDYPEPGEV--------SQDVIA 69

  Fly    99 ISNEDR--------QEIASCNSILTFSSRLKPEQLDNE---LDMHITFNTND------------- 139
            |.|..|        :..|||.     ..|.:.|....|   :|| :.:.|::
 Frog    70 IYNSTRDLLQEKANERAASCE-----RERSEDEYYAKEVYKIDM-LPYYTSENVIPPSYTTPYFR 128

  Fly   140 -VPVDLS--------LVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQDFS--YRILGS-VNTTS 192
             |..|:|        ||:|..|:::..:...|.:...:.:|:.|.::...|  .|.:.| |..|.
 Frog   129 IVRFDVSSMEKNASNLVKAEFRVFRLMNPKARVSEQRIELYQILKSKDLASPTQRYIDSKVVKTR 193

  Fly   193 SQRGWLEFNLTDTLRYWLHNKGLQRRNELRISIGDSQLSTF--AAGLVTPQASRTSLEPFIVG-- 253
            ::..||.|::|:.:..|||:|  .|....:||: .....||  :...:.|..|. .||....|
 Frog   194 AEGEWLSFDVTEAINEWLHHK--DRNLGFKISL-HCPCCTFIPSNNYIIPNKSE-ELETRFAGID 254

  Fly   254 ----YFNGPE--------------LLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVD---LYRPP 297
                |...|:              ||:.:...|.:.....||         ....:|   .:|..
 Frog   255 DAYMYAGDPKTKSRKKHTGRTPHLLLMLLPSYRLESQQSSRR---------KKRALDAAYCFRNV 310

  Fly   298 Q-SCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHL- 360
            | :|......:|||......|:..||.:.|.||.|.|.:...:.   |.|:.|.:|.:...|..
 Frog   311 QDNCCLRPLYIDFKRDLGWKWIHEPKGYNANFCAGACPYLWSSD---TQHSRVLSLYNTINPEAS 372

  Fly   361 PKPCCVPTVLGAITILRYL-NEDIIDLTKYQKAVAKECGC 399
            ..||||...|.::|||.|: |:..|:  :....:.|.|.|
 Frog   373 ASPCCVSQDLDSLTILYYIGNKPKIE--QLSNMIVKSCKC 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	61/259 (24%)
		TGF_beta_BMP5_like	299..400	CDD:381639	31/103 (30%)
tgfb2	XP_002936067.1	TGFb_propeptide	21..228	CDD:459906	54/226 (24%)
		TGF_beta_TGFB2	314..410	CDD:381655	30/100 (30%)