Protein Alignment scw and gdf2

DIOPT Version :10

• Sequence 1: NP_524863.3
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_002940692.2
• Gene: gdf2 / 100485289
• XenbaseID: XB-GENE-478184
• Length: 410
• Species: Xenopus tropicalis
• Alignment Length: 422
• Identity: 99/422 - (23%)
• Similarity: 177/422 - (41%)
• Gaps: 89/422 - (21%)

  Fly    23 NNHIEMPIYQKRP--------LSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVYNEISEDQ 79
            |:|..   |:::|        .:.:.|.:..|:|...|   ::..:.....:|::|:||..|||:
 Frog    32 NHHRH---YEEKPEDIMSLFMENTKKEFLWGLNLSGVP---SQDKIKKMPPQFMIELYNRFSEDK 90

  Fly    80 EPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSR--LKPEQLDNELDMHITFNTNDVPV 142
            ..|.|                         .|.|.:|::.  |....|::....||......:|.
 Frog    91 TLKPV-------------------------SNIIRSFNAEDILSSSALEDTFQSHIVLFNVSIPQ 130

  Fly   143 DLSLVQAMLRIYKQPSLVDRRANFTVSVYRKLDNRQDFSYRILGSV--NTTSSQRGWLEFNLTDT 205
            ...|.:|.|::|..   :.::.:..:.||..|......:.|...|:  :....:.|||..|:|..
 Frog   131 HEELTEAELKMYVS---LGKKYHGHLLVYDILYTEPFENLRYPKSLIESKIIERSGWLSINVTRA 192

  Fly   206 LRYWLHNKGLQRRNELRISIGDSQ-----------------LSTFAAGLVT--------PQASRT 245
            ::.|:.:..:.::  |.|.:|.::                 .|::...|:.        ||.::.
 Frog   193 VKRWITSSRITKK--LEIFLGSNKPLNSCLRLQDNRRGVKINSSYPPVLLVFSDDKWSKPQKTKM 255

  Fly   246 SLEPFIVGYFN-GPELLVKIQKLRFKRDLEKR---RAGGGSPPPPPPPPVDLYRPPQSCERLNFT 306
            ..:..|....| |.:.:.|...:::..:..|.   ..|.|.      ..|...:....|.:.:..
 Frog   256 ERKEIIFHEENIGTQTVSKKNTVKYANNGHKNWNFGLGNGK------MRVKRSQATNYCRKSSLK 314

  Fly   307 VDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLP-KPCCVPTVL 370
            |:||::...:|:|:|.:::||.|.|.|.:||...:..|.|||:|||||.|.|.:. |.|||||.|
 Frog   315 VNFKDIGWDSWIISPPEYDAYECKGECYYPLTDNLTPTKHAIIQTLMHFKNPKITRKACCVPTQL 379

  Fly   371 GAITILRYLNEDIIDLTKYQ---KAVAKECGC 399
            ..|:|. |:::..|...||:   ..||| |||
 Frog   380 EPISIF-YIDDKGIPTMKYKYEGMKVAK-CGC 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_524863.3	TGFb_propeptide	39..254	CDD:480997	44/243 (18%)
		TGF_beta_BMP5_like	299..400	CDD:381639	44/105 (42%)
gdf2	XP_002940692.2	TGFb_propeptide	53..208	CDD:480997	37/187 (20%)
		TGF_beta_BMP9	306..410	CDD:381670	44/106 (42%)