Protein Alignment scw and gdf5

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_002662587.1
• Gene: gdf5 / 100334210
• ZFINID: ZDB-GENE-990415-39
• Length: 474
• Species: Danio rerio
• Alignment Length: 430
• Identity: 105/430 - (24%)
• Similarity: 173/430 - (40%)
• Gaps: 83/430 - (19%)

  Fly    13 AASATTYVTTNNHIEMPIYQK--RPLSEQMEMIDILDLGDRP---RRQAEPNLHNSAS------- 65
            ||:..:..:..:|.:....||  .|.:.:.....|..:...|   |.::...|.||..
Zfish    84 AANLASPSSIQHHSKAASTQKSSAPAAVRAAPAGIKSIAPAPSHLRMKSAVKLENSEEPKHPLVI 148

  Fly    66 --KFLLEVYNEISEDQEPKEVLHQRHKRSLDDDILISNEDRQEIASCNSILTFSSRLKPEQLDNE 128
              .::|.:|..::.......|||                   |....|:|.:|..|.:.|:....
Zfish   149 PHDYMLSLYWSLTSGDVNTSVLH-------------------EAGMANTITSFVDRGQDERAPLL 194

  Fly   129 LDMHITFNTNDVPVDLSLVQAMLRIYKQPSLVDRRANFT--VSVYRKLDNRQDFSYRILGSVNTT 191
            ......||.:.:..: .|:.|.|||.::..:..|:|.|:  ::|.|........:..:|......
Zfish   195 RRQRYVFNISSMEKE-GLLGAELRILRKKHMDSRKATFSEGMAVLRLFTCASGKNAAVLLQARPF 258

  Fly   192 SSQRG--WLEFNLTDTLRYWLHNKGLQRRNELRISIG--------DSQLSTFAAGLVTPQASRTS 246
            .|...  |..|::      |...|..:...:|.:.:.        |.:|      |...:|.|.:
Zfish   259 DSHSASYWEVFDI------WKVFKNFRNTPQLCLELDAVDHGRPLDLRL------LGLSRAGRQT 311

  Fly   247 LEP--FIV-------GYF-------NGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYR 295
            .|.  |:|       |.|       :|.:.....:.|..:|.:  |||    |.|....|:.  .
Zfish   312 KEKAFFVVFGRTKKRGLFYNEIKARSGHDNKTVYEYLFTQRRM--RRA----PLPRGKKPIK--N 368

  Fly   296 PPQSCERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPH- 359
            |.|.|.|....|:|||:...:|:|||.::||:.|.|.|:||:.:.:..|||||:||||:...|.
Zfish   369 PKQRCNRKQLHVNFKEMGWDDWIIAPLEYEAFHCDGVCDFPIRSHLEPTNHAIIQTLMNSMDPRS 433

  Fly   360 LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            .|..|||||.|..|:||...:.:.:...:|:..|.:.|||
Zfish   434 TPPTCCVPTRLSPISILYIDSANNVVYKQYEDMVVESCGC 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	44/247 (18%)
		TGFB	300..400	CDD:214556	42/101 (42%)
gdf5	XP_002662587.1	TGFb_propeptide	138..320	CDD:279078	39/213 (18%)
		TGF_beta	371..473	CDD:278448	41/101 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810