Protein Alignment scw and gdf5

DIOPT Version :9

• Sequence 1: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: NP_001128589.1
• Gene: gdf5 / 100189547
• XenbaseID: XB-GENE-481784
• Length: 496
• Species: Xenopus tropicalis
• Alignment Length: 449
• Identity: 113/449 - (25%)
• Similarity: 186/449 - (41%)
• Gaps: 110/449 - (24%)

  Fly    13 AASATTYVTTNNHIEMPIYQKRPLSEQMEMIDILDLGDRPRRQAEPNLHNSASKFLLEVY----- 72
            |:.|..:|.|.|      .:.|...|::|         .||   .|::.:.||..|:.::
 Frog    95 ASRANPHVKTGN------AENRQSGEKIE---------TPR---PPHVTSKASTKLINIHADSAG 141

  Fly    73 -------NEISEDQEP---KEVLHQRHKRSLDDDILISNEDRQ--------EIASCNSILTFSSR 119
                   |.::|.::.   |..|...|:..|.....:|:.:|:        |....|:|.:|..:
 Frog   142 FKPKRPPNPLTEKEQKDAFKHPLITPHEYMLSLYRTLSDVERKGINGSLKLEAGLANTITSFIDK 206

  Fly   120 LKPEQLDNELDMHITFNTNDVPVDLSLVQAMLRIY-KQPSLVDRRAN-----FTVSVYRKLDNRQ 178
            .:.|::........||:.:.:..| .|:.|.|||. |:|  :|.:.|     :.:.:|....|::
 Frog   207 GQDERMAAARRQKYTFDISALEKD-GLLGAELRILRKRP--IDAKLNSAGKLWQIKLYSCPANKK 268

  Fly   179 D---FSYRILGSVNTTSSQRGWLEFNLTDTLRYWLHNKGLQRRNELRI----------SIG---- 226
            .   ...|.|||::|..    |..|::...  |......:|...||.:          |:|
 Frog   269 SATLLDSRPLGSIDTPK----WEVFDIWKL--YKNFKNSVQLCFELEVLDKGKPADLRSVGFNRT 327

  Fly   227 DSQLSTFAAGLVTPQASRTSLEPFIVGYFNGPELLVKIQKLRFKRD-----------LEKRRAGG 280
            ..|.:..|..||..:..:..|      :||  |:     |.|..:|           ..||||
 Frog   328 GRQTNEKAIFLVFGRTKKRDL------FFN--EI-----KARSGQDDKTVYEYLFNQRRKRRA-- 377

  Fly   281 GSPPPPPPPPVDLYRPPQS----CERLNFTVDFKELHMHNWVIAPKKFEAYFCGGGCNFPLGTKM 341
                  |.......||.::    |.:....|:||::...:|:|||.::|||.|.|.|.|||.:.:
 Frog   378 ------PLSTRQGKRPNKNSKARCSKKPLHVNFKDMGWDDWIIAPLEYEAYHCEGLCEFPLRSHL 436

  Fly   342 NATNHAIVQTLMHLKQPH-LPKPCCVPTVLGAITILRYLNEDIIDLTKYQKAVAKECGC 399
            ..||||::||||:...|. .|..|||||.|..|:||...:.:.:...:|:..|.:.|||
 Frog   437 EPTNHAVIQTLMNSMDPETTPPTCCVPTRLSPISILYTDSANNVVYKQYEDMVVESCGC 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	52/260 (20%)
		TGFB	300..400	CDD:214556	41/101 (41%)
gdf5	NP_001128589.1	TGFb_propeptide	142..328	CDD:279078	40/194 (21%)
		TGFB	395..496	CDD:214556	41/101 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910