Protein Alignment retn and arid4a

DIOPT Version :10

• Sequence 1: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_012824464.2
• Gene: arid4a / 733818
• XenbaseID: XB-GENE-983782
• Length: 1309
• Species: Xenopus tropicalis
• Alignment Length: 785
• Identity: 140/785 - (17%)
• Similarity: 263/785 - (33%)
• Gaps: 259/785 - (32%)

  Fly   254 NSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLP 318
            :|:|:.....:.:..|.||.    ||:.:...:  |..|..:|..||..|:.||:.||||||:.|
 Frog   272 SSSSDEEDGEDDACDSDQNK----EEEVETEPE--EEADPAERDIFLQQLYKFMEDRGTPINKPP 330

  Fly   319 IMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYE-- 381
            ::....|:|::|:.||..:||..::.:..:|::|...|.:|...::|::.::|.|.||||.:|
 Frog   331 VLGYKDLNLFKLFRLVYQQGGCDNIESGAVWKQIYMDLGIPILNSAASYNVKTAYKKYLYGFEEY 395

  Fly   382 CEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPMTPISRPSLPGGMQQMSPLALVTHAA 446
            |...|:                       |:..:|:..| .||..|.    :::..|:
 Frog   396 CRSANI-----------------------QFRTIHHNDP-KPIEEPK----VEEEKPM------- 425

  Fly   447 VANNQQAQAAA----AAAAAHHRLMGAPAFGQMPNLVKQEIESRMM------------------- 488
             .:::|.:.|:    |..........:..:|      |:|.|:.|.
 Frog   426 -ESSEQKETASPLLDAKMKEEDESDSSSEYG------KEETETEMKSPRGRRRCAFNAFSVVTDV 483

  Fly   489 -----------------EYLQLIQAKKEQGMPPV--------LGGNHPHQQQHSQQQQQQQHHHQ 528
                             |.|...:.|:|....||        .|.....:|..|:::..:.....
 Frog   484 EDSDTRKDNNKENKDIEEDLNKTEEKEEDESTPVRRSLQCRAKGDQKTKKQDESERESDEDDEKP 548

  Fly   529 QQQQQQSQQQHHLQQQRQRSQSPDL---SKHEALSAQVALWHMYHNNNSPPGSAHTSPQQREALN 590
            .:.::.|:.:...:::.:.::..|.   :|.:....:.....:|..|     ...|.....|.|.
 Frog   549 CEGKEDSEHKGETEEEDEDTEDRDYLAGTKVKVKYGRGKTQKIYEAN-----IKSTEVDGGELLY 608

  Fly   591 L----------------------SD-SPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGS 632
            |                      || ..|.....|:.:.::...|..:.|.:.....||.|....
 Frog   609 LVHYYGWNVRYDEWVKADRIIWPSDKGGPKKKQKKKTKNKDENEEKKEDDKRSKRGRPPLKSAHQ 673

  Fly   633 GLLPPGFP-------ANFYLNPHNMAAVAA----------------AAGFHHPSMGHQQDAASEG 674
            ..:..|.|       .....|..|..:.::                ::|.:.........:.||.
 Frog   674 TNMTCGLPKTPTSEGKTSVKNMRNSLSDSSSLSNGLEGSARRRTRRSSGLYDSDRCSNDSSTSES 738

  Fly   675 EPEDDYAHG----------------------------------------EHNTTGNSSSMHDD-S 698
            |.::.....                                        ||:.|..:.::..: .
 Frog   739 ESDETSEKASVKEEEVLPKAEEEPENILSLVDISPVKEVPPVICLLKDPEHSPTKPAETLKQEVE 803

  Fly   699 EPQQMNGHHHHQTHHLD----------------KSDDSAIENSPTTSTTTGGSVGHRHSSPVSTK 747
            |.:|:...:..||..|:                |:.||::||:...|.|...::...|....:..
 Frog   804 ESEQIVQIYGKQTEELEEIKEAEHLPKSKGRRSKTKDSSVENTKCLSATQEDTLVEPHVEEDTLD 868

  Fly   748 KKGGAKPQSGGKDVPTEDKDASSSGKLNPLETLSLLSGMQFQVARNGTGDNGEPQLIVNLELNGV 812
            ....:..||  |::|...|:|.....               |:|:               |..|:
 Frog   869 LPSLSPLQS--KELPFTPKEAELPND---------------QLAQ---------------EKKGL 901

  Fly   813 KYSGVLVANVPLSQS--ETRTSSPCHAEAPT-VEEEKDEEEEEEPKAAEEESHRSPVKQENE--D 872
            |       ..||.||  :.:..:.|..|.|. |.|||.||..|    |:|  |.:.:.::.|  :
 Frog   902 K-------RKPLEQSSPDKKLRTECDPELPVIVAEEKTEENNE----AQE--HFNTIHEDEELPN 953

  Fly   873 VDQDM 877
            |:::|
 Frog   954 VNEEM 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	ARID_Dri-like	277..401	CDD:350645	38/125 (30%)
arid4a	XP_012824464.2	Tudor_ARID4A_rpt1	4..61	CDD:410530
		Tudor_ARID4_rpt2	62..114	CDD:410461
		RBB1NT	170..260	CDD:462390
		ARID	307..393	CDD:355778	31/85 (36%)
		PLN00104	524..>628	CDD:215056	12/108 (11%)
		CBD_RBP1_like	577..633	CDD:350843	7/60 (12%)