Protein Alignment retn and Arid5b

DIOPT Version :10

• Sequence 1: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_006514192.1
• Gene: Arid5b / 71371
• MGIID: 2175912
• Length: 1214
• Species: Mus musculus
• Alignment Length: 880
• Identity: 159/880 - (18%)
• Similarity: 265/880 - (30%)
• Gaps: 352/880 - (40%)

  Fly   247 EARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQVRQLYEINDDPKRKE--FLDDLFSFMQK 309
            |||.......:|.:...:.||          ||:.|     ..|.::.:..|  ||..|:.:|::
Mouse   312 EARSALTKPKNNHNNCKKTSN----------EEKPK-----LSIGEECRADEQAFLVALYKYMKE 361

  Fly   310 RGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYM 374
            |.|||.|:|.:....::|:.::......||...:..::.|:.|...|......||||...|..|.
Mouse   362 RKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYE 426

  Fly   375 KYLYPYE----------------CEKKNLSTPAELQAAIDGNRREGRRSSYGQYEAMHNQMPM-- 421
            :.:.|||                .:::|.:...|.:..:.||:|..:..:..:.|..:...|.
Mouse   427 RLILPYERFIKGEEDKPLPPIKPRKQENNTQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDT 491

  Fly   422 -----------------------------------------TPISR------------------- 426
                                                     .|:||
Mouse   492 SEVSSEQRKEEETLNHKSAPEPLPAPEVKGKPEGHKDLGARAPVSRADPEKANETDQGSNSEKEA 556

  Fly   427 ------------PS-----------LPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMG 468
                        ||           .||..:|  |||..: ..:.:.|:|:......:....|.|
Mouse   557 EEMGDKGLAPLLPSPPLPPEKDSAPTPGAGKQ--PLASPS-TQMDSKQEAKPCCFTESPEKDLQG 618

  Fly   469 AP----------------------------------------------AFGQMPN-LVKQEI--- 483
            ||                                              |..|.|. ||.|..
Mouse   619 APFSSFSATKPPLTSQNEAEEEQLPATANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMF 683

  Fly   484 ----------ESRMMEYLQLIQAKKEQG-MPPV-------------LGGNHPHQQQHSQQQQQQ- 523
                      |:..:.|..|:.::...| |.|:             |..::|:........:::
Mouse   684 KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKL 748

  Fly   524 -----------QHHHQQQQQQQSQQQ----HHLQQ-----QRQRSQSPDLSKHEALSAQVALWHM 568
                       |.||.|.....:..:    .|:|.     ...|....|:.||:.||.
Mouse   749 IAREDLCSGLSQGHHSQSSDHTAVSRPSVIQHVQSFKNKASEDRKSINDIFKHDKLSR------- 806

  Fly   569 YHNNNSPPGSAHTSPQQREAL-NLSDSPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGS 632
                    ..||.....:..| :|:||    ..:|:|.:        :..||.::     ||..|
Mouse   807 --------SDAHRCGFSKHQLGSLADS----YILKQETQ--------EGKDKLLE-----KRAVS 846

  Fly   633 GLLPPGFPANFYLNPHNMAAVAAAAGFHHPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMH-- 695
            ....|.|.|:||.:||          .|  |:               |.|.||:.....||.:
Mouse   847 HAHVPSFLADFYSSPH----------LH--SL---------------YRHTEHHLHNEQSSKYAA 884

  Fly   696 DDSEPQQMNG----HHHHQTHHL---------DK---SDDSAIENSPTTST-------TTGGSVG 737
            .|:..:..||    |.|.:..|:         ||   :.:::.::.||..:       .|...:|
Mouse   885 RDAYQESENGAFLSHKHPEKIHVNYLASLHLQDKKVAAAEASTDDQPTDLSLPKNPHKLTSKVLG 949

  Fly   738 HRHSSPVSTKKKGGAKPQ---------------------SGGKDVPTEDKDASSSGKLNP--LET 779
            ..||:..|.:.||.::.|                     ||.|..|   :..:.|||.:.  ||.
Mouse   950 LAHSTSGSQEIKGASQFQVVSNQSRDCHPKACRVSPMTMSGPKKYP---ESLARSGKPHQVRLEN 1011

  Fly   780 LSLLSGMQFQVARNGTGDNGEPQLI-----VNLELNGVKYSGVLVANVPLSQSETRTSSPCHAEA 839
            ...:.||...:...    ...||.|     :...|..:        ::.::..:.|..||.....
Mouse  1012 FRKMEGMVHPILHR----KMSPQNIGAARPIKRSLEDL--------DLVIAGKKARAVSPLDPAK 1064

  Fly   840 PTVEEEKDEEEEEE--------PKAAEEESHRSPV 866
            ....:||..|:|.|        ...|..|.|:.|:
Mouse  1065 EASGKEKASEQESEGNKGAYGGHSGAASEGHKLPL 1099

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	ARID_Dri-like	277..401	CDD:350645	33/141 (23%)
Arid5b	XP_006514192.1	ARID_ARID5B	347..441	CDD:350649	26/93 (28%)
		PTZ00121	<437..>562	CDD:173412	10/124 (8%)