Protein Alignment retn and Arid3b

DIOPT Version :9

• Sequence 1: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: NP_001366282.1
• Gene: Arid3b / 56380
• MGIID: 1930768
• Length: 568
• Species: Mus musculus
• Alignment Length: 518
• Identity: 176/518 - (33%)
• Similarity: 233/518 - (44%)
• Gaps: 154/518 - (29%)

  Fly   239 PTAAPSGKEARHFAANSASNSSTSSEASNSSQQNNGWSFEEQFKQ-------------------- 283
            |..:|.|::.:......||.:..|...:...    .||.:||.||
Mouse   142 PGLSPQGQQTKEDHTKDASKAPPSVPTAGQP----SWSLDEQLKQNGALAWSDDADGGRGREISR 202

  Fly   284 -VRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKK 347
             ..:|||::.||:|||||||||.|||||||||||:|||||.:||||.||.||..:||||::||||
Mouse   203 DFAKLYELDGDPERKEFLDDLFIFMQKRGTPINRIPIMAKQILDLYMLYKLVTEKGGLVEIINKK 267

  Fly   348 LWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREGRRSSYGQY 412
            :|:||.|||:||:||||||||||||||||||.||||||.||:|||||||||||||||||.||..
Mouse   268 IWREITKGLNLPTSITSAAFTLRTQYMKYLYAYECEKKALSSPAELQAAIDGNRREGRRPSYSS- 331

  Fly   413 EAMHNQMPMTPISRPSLPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQMPN 477
                           ||.|    .||.|....||.|    |.|||:||:|     |.||....|.
Mouse   332 ---------------SLFG----YSPAAAAAAAAAA----AAAAASAASA-----GTPALLSSPK 368

  Fly   478 LVKQEIESRMMEYLQLIQA----------------KKEQGMP-PV-------------LGGNHPH 512
            :        ....|.|..:                :|..|:| ||             ..||.|.
Mouse   369 I--------RFSILGLGSSSGTSASSPRIPPASTLRKGDGVPVPVPNRLAVSGTLAGQQAGNRPG 425

  Fly   513 QQQHSQQQQQQQHHHQQQQQQQSQQQHHLQQQRQRSQSPDLSKHEALSAQVALWHMYHNNNSPPG 577
            ..:|.:::.:.....:::..:.|:::..|.||..:.....:::...:..::        |.....
Mouse   426 PLEHLRERLESGEPPEKKASRLSEEEQRLVQQAFQRNLFSMARQLPMKIRI--------NGREDR 482

  Fly   578 SAHTSPQQREALNLSDSPPNLTNIKREREREPTPEPVDQDDKFVDQPPPAKRVGSGLLPPGFPAN 642
            :..::|    ||||:.|  |:.:|...         ||.|.          ...:|:|
Mouse   483 AEPSAP----ALNLTTS--NIGSINMS---------VDIDG----------TTYTGVL------- 515

  Fly   643 FYLNPHNMAAVAAAAGFHHPSMGHQQDAASEGEPEDDYAHGEHNTTGNSSSMHDDSEPQQMNG 705
            |...|    .|...||....|:|   .:||               :.||||.|....|....|
Mouse   516 FAQKP----VVHLIAGSTPQSIG---SSAS---------------SSNSSSSHCSPSPTSSRG 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	BRIGHT	294..386	CDD:128777	73/91 (80%)
Arid3b	NP_001366282.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..174		6/35 (17%)
		Interaction with RB1. /evidence=ECO:0000250	201..374		119/209 (57%)
		ARID_ARID3B	202..327	CDD:350643	96/124 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	378..403		2/24 (8%)
		Interaction with ARID3A. /evidence=ECO:0000250	495..518		9/50 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	529..568		11/46 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846991
Domainoid	1	1.000	150	1.000	Domainoid score	I4373
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	255	1.000	Inparanoid score	I3158
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001099
OrthoInspector	1	1.000	-	-		otm42916
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15348
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1374
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.970