DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment retn and ARID2

DIOPT Version :9

Sequence 1:	NP_788434.1	Gene:	retn / 45976	FlyBaseID:	FBgn0004795	Length:	911	Species:	Drosophila melanogaster
Sequence 2:	NP_689854.2	Gene:	ARID2 / 196528	HGNCID:	18037	Length:	1835	Species:	Homo sapiens

Alignment Length:	91	Identity:	36/91 - (39%)
Similarity:	51/91 - (56%)	Gaps:	2/91 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly   293 DPKRK--EFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKG 355
            |.:||  .|||:|..|...||:|..::|.:....|||:.||..|...||...|..|..|.||::.
Human    11 DERRKGLAFLDELRQFHHSRGSPFKKIPAVGGKELDLHGLYTRVTTLGGFAKVSEKNQWGEIVEE 75

  Fly   356 LHLPSSITSAAFTLRTQYMKYLYPYE 381
            .:.|.|.::|||.|:..|::||..||
Human    76 FNFPRSCSNAAFALKQYYLRYLEKYE 101

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	BRIGHT	294..386	CDD:128777	35/90 (39%)
ARID2	NP_689854.2	ARID	19..101	CDD:279697	31/81 (38%)
		LXXLL	313..317
		RFX_DNA_binding	521..601	CDD:280427
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	819..844
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	894..919
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	962..1057
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1266..1287
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1295..1314
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1321..1341
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1488..1522
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1572..1629
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1703..1728
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2744
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810