Protein Alignment retn and ARID3C

DIOPT Version :10

• Sequence 1: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_047278737.1
• Gene: ARID3C / 138715
• HGNCID: 21209
• Length: 562
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 170/505 - (33%)
• Similarity: 222/505 - (43%)
• Gaps: 179/505 - (35%)

  Fly   181 NGSSYNG------------GTTPTNSSNSNAT-------TNGGGTAGPGGTGGSGGGGGGGGGGG 226
            :|.|:.|            |..|..:::|.|:       ..|||:|.||.:.|.|..|||...|.
Human    49 SGRSHRGLSPCAPPALPRSGPAPAAAASSAASERTAARGAQGGGSAPPGPSRGQGRLGGGRSKGS 113

  Fly   227 G----GVGGH--QFSFAS--------PTA------------------------------------ 241
            .    |..||  |.:.:|        |:|
Human   114 AVETPGAAGHARQAALSSGSRLVPGTPSAGGLRLEAVMEALQKQQAARLAQGVGPLAPACPLLPP 178

  Fly   242 -----------APSG----------------KEARHFA-----ANSASNSSTSSEASNSSQ---- 270
                       ||.|                :|.|..|     |...|.......:|.|||
Human   179 QPPLPDHRTLQAPEGALGNVGAEEEEDAEEDEEKREEAGAEEEAAEESRPGAQGPSSPSSQPPGL 243

  Fly   271 QNNGWSFEEQFKQVRQLYEINDDPKRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVI 335
            ..:.|::|||||   ||||::.|||||||||||||||||||||:||:|||||.|||||.|:.||.
Human   244 HPHEWTYEEQFK---QLYELDADPKRKEFLDDLFSFMQKRGTPVNRVPIMAKQVLDLYALFRLVT 305

  Fly   336 ARGGLVDVINKKLWQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYECEKKNLSTPAELQAAIDGN 400
            |:||||:|||:|:|:|:.:||.||::||||||||||||||||||||||.:.||:|.|||||||.|
Human   306 AKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQYMKYLYPYECETRALSSPGELQAAIDSN 370

  Fly   401 RREGRRSSY--------------GQYEAMHNQMPMTPISRPSLPGGMQ------------QMSP- 438
            ||||||.:|              |..:......|..|.::.| ||..|            |:||
Human   371 RREGRRQAYTATPLFGLAGPPPRGAQDPALGPGPAPPATQSS-PGPAQGSTSGLPAHACAQLSPS 434

  Fly   439 -------------LALVTHAAVANNQQAQAAAAAAAAHHRLMG---------APAF---GQMP-- 476
                         |||....|:...::..|..........|||         .|:|   |::|
Human   435 PIKKEESGIPNPCLALPVGLALGPTREKLAPEEPPEKRAVLMGPMDPPRPCMPPSFLPRGKVPLR 499

  Fly   477 --------NL-------VKQEIESRMMEYLQLIQAKKEQGMPPVLGGNHP 511
                    ||       :...:|...:.|..::.|:: |.:|...|..:|
Human   500 EERLDGPLNLAGSGISSINMALEINGVVYTGVLFARR-QPVPASQGPTNP 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	ARID_Dri-like	277..401	CDD:350645	92/123 (75%)
ARID3C	XP_047278737.1	ARID_ARID3C	251..377	CDD:350644	98/128 (77%)