Protein Alignment retn and htk

DIOPT Version :10

• Sequence 1: NP_788434.1
• Gene: retn / 45976
• FlyBaseID: FBgn0004795
• Length: 911
• Species: Drosophila melanogaster
• Sequence 2: XP_061502837.1
• Gene: htk / 1269724
• VectorBaseID: AGAMI1_000086
• Length: 2575
• Species: Anopheles gambiae
• Alignment Length: 1146
• Identity: 209/1146 - (18%)
• Similarity: 351/1146 - (30%)
• Gaps: 430/1146 - (37%)

  Fly    28 DLSHGDR------TDDEMRDCDSV-----DGEHHQLSAKAAIAARLSHTVSGGGGSFASPEPQTE 81
            ::.|.:|      |..:::||...     ||:...| .::|:..:       .|..|...|...:
Mosquito    68 EVKHPERKEYVEATLTKIQDCSQYTVVFDDGDITTL-RRSALCLK-------SGRHFNESETLDQ 124

  Fly    82 LPLSHHHQLPPNHPLN-ALGSFMGIGGLHSIPNLQHSDVLEKLKMQVRDMKVGLMEQDYAAAAHA 145
            |||:|     |.|..| .:|...|....|.:|: :.||                 |:|.
Mosquito   125 LPLTH-----PEHFGNPVIGGRRGRRSRHLLPD-ESSD-----------------EEDE------ 160

  Fly   146 AAFGANMLPTTISSGFPLPHNSVAFGHVTSSPSGGNGSSYNGGTTPTNSSNSNATTNGGGTAGPG 210
                    ||                  |.|.|..:....|.|......::.|...|......||
Mosquito   161 --------PT------------------THSRSNASDKEENIGKVVCVETSDNKKKNPKENWFPG 199

  Fly   211 GTGGSGGGGGGGGGGGGGVGGHQFSFASPTAAPS-----------------------GKEARHFA 252
                                    ...:|||..:                       .|||..|.
Mosquito   200 ------------------------LVVAPTAQDTVRIRVKDEYLVRSFKDGRYYTVPKKEATEFT 240

  Fly   253 ANSASNSSTSSEASNSSQQNNG-----WSFEEQF---------KQVRQLYEINDDP--KRKEFLD 301
            .:|.:.|..::.::.....:|.     |..|..|         .|..:....:|:|  ::..|:.
Mosquito   241 RDSVNKSEAAAVSAAIEYMDNDVLPPHWDREALFGTSGSCSDSDQELETDSSDDEPTEEKDHFVA 305

  Fly   302 DLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKLWQEIIKGLHLPSSITSAA 366
            .|:.||..||||:|:.|.:....:|||.|:..|....|...|.::..|::|  .|.|..|..:|:
Mosquito   306 QLYKFMDDRGTPLNKAPSITNRDVDLYRLFRAVQKLHGYNRVTSQNQWKQI--ALRLGFSPATAS 368

  Fly   367 FT--LRTQYMKYLYPYECEKKNLSTPAELQAAIDGNRREG----------RRSSYGQYEAMHNQM 419
            .|  ::..|.|:|:.:|                :.||:.|          |........|...|.
Mosquito   369 ITNLVKQAYKKFLFSFE----------------EFNRKLGCTMVPHPKTSRTKGRSLVRASSVQS 417

  Fly   420 PMTPISRPSLPGGMQQMSPLALVTHAAVANNQQAQAAAAAAAAHHRLMGAPAFGQ---------- 474
            |..| .:..|....::.:.:|....:|.|::..|.||||||||......|.|...
Mosquito   418 PKLP-EKEKLLTAKEKAASVAAADASAKASSSSAAAAAAAAAAASAAAAAAAAAAATEASNSAVE 481

  Fly   475 ----------------MPNLVKQEIESRMMEYLQLIQ---------------------------- 495
                            .|:..|:::....::  .|:.
Mosquito   482 ESGNTSESSAAESAVLRPSSTKRKVGGGKVK--ALVDKFEEKEKERDKEKSVGKGGGGESSGSSG 544

  Fly   496 -AKKEQGMPPV-------LGGN-HPHQ----QQHSQQQQQQQHHHQQQQQQQS------------ 535
             :|||:.:.|.       |||. .|.:    ::..::::.......::.::::
Mosquito   545 GSKKEESVTPASAKKEKQLGGKAKPAETTVVEKRGRKRKDADSVDSKKDERETTATGGSSASTGG 609

  Fly   536 ------QQQHHLQQQRQ------------------------------RSQSP------------- 551
                  |.:|....:::                              ||.||
Mosquito   610 ASSNVKQDKHPASSRKEDGGPPNSGSGGGGGGGGSSGNGSGPGSGGGRSISPGSAVSGGTVPDFP 674

  Fly   552 -----------DLSK--HEALSAQVAL-------------WHMYH-------------------- 570
                       |..|  :||...::|.             |:..:
Mosquito   675 IEVGDKLKVYYDEQKVTYEAKVIEIAKQEGNPIYLVHYTGWNTRYDEWVRKERIAENLTNSKTKK 739

  Fly   571 ---NNNSPPGSAHTSPQQREA-----LNLSDSPPNL-----TNIKREREREP----TPEPVDQD- 617
               :.|:|.....::.|...:     |...|..|.:     .|.|.|:...|    ||.....:
Mosquito   740 GKSSGNTPTAGGPSTKQASSSNAGSTLTAGDKTPKIGKRSRGNSKGEQSSGPGGNSTPRSTTPNV 804

  Fly   618 --DKFVDQPP---PAKRVGSGLLPPGFPANFYLNPHNMAAVAAAAGFH-------HPSMGHQQDA 670
              :|....|.   |..|.||..          ....:::|.|||||..       ..|:....|.
Mosquito   805 GRNKSPATPSNRRPLTRGGSSA----------ATGSSLSASAAAAGRRTSNNTDISSSLSVPTDP 859

  Fly   671 ASEGEPEDD-------YAHGEHNTTGNSSSMHDDSEPQQMNGHHHHQTHHLDKSDDSAI---ENS 725
            .:..:.:.|       ..:...:||.::||:...|...:::     .|.....|.|:|.   |.|
Mosquito   860 DNTSDTDSDEPMLKKCTTNSTSSTTSSNSSISISSTSTKVS-----TTAEAGSSSDAAAISDEFS 919

  Fly   726 PTTSTTTGGSVG--------HRHSSPVSTKKKGGAK---PQSGGKDVPTEDKDASSSGKLNPLET 779
            ...|...||.||        ....:.:.::.||..:   |.|...|..|.....:.:.:..|..:
Mosquito   920 NGASKGVGGGVGVGGVGGGRDYDLNQIRSELKGFKELKSPGSPASDTTTTTTTTAGAAEGGPNSS 984

  Fly   780 LSLLSGMQFQVARNGTGDNGEPQLIVNLELNGVKYSGVLVANVPLS--QSETRTSSPCHAEAPTV 842
            .|:....:..:.:.      ||.|   |....||.| |..:|.||:  :.|...:.|...|..||
Mosquito   985 SSITDVPKHLIPKQ------EPNL---LSTTDVKES-VSSSNTPLATIKKELAAAVPIKEEESTV 1039

  Fly   843 EEEKDEEEE--EEPKAAEEESHRSPVKQENED-----VDQD 876
            .||.||.|:  |....:||:|.:|..|..:..     ||.|
Mosquito  1040 TEEDDEPEKSSESETLSEEDSSQSSNKAFSSSPITTMVDSD 1080

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
retn	NP_788434.1	ARID_Dri-like	277..401	CDD:350645	33/136 (24%)
htk	XP_061502837.1	None