Protein Alignment S6KL and Prkci

DIOPT Version :10

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_114448.1
• Gene: Prkci / 84006
• RGDID: 620961
• Length: 596
• Species: Rattus norvegicus
• Alignment Length: 280
• Identity: 93/280 - (33%)
• Similarity: 144/280 - (51%)
• Gaps: 41/280 - (14%)

  Fly   157 DLYRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFI 221
            ||.|:   :.:|::..|..|..|. ..:.||:||:||..:.:|..:..::.|..:.:...:|||:
  Rat   255 DLLRV---IGRGSYAKVLLVRLKK-TDRIYAMKVVKKELVNDDEDIDWVQTEKHVFEQASNHPFL 315

  Fly   222 VKQIDLWQNRHNLHILSEYVPNGEL---FSKITHFSIDLVRLYIGEIALALDFLHNAGIIYRDAK 283
            |.....:|....|..:.|||..|:|   ..:......:..|.|..||:|||::||..||||||.|
  Rat   316 VGLHSCFQTESRLFFVIEYVNGGDLMFHMQRQRKLPEEHARFYSAEISLALNYLHERGIIYRDLK 380

  Fly   284 PENILLTEQFHIKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWALGVIACQ 347
            .:|:||..:.||||||:|:.| .|:.|..|.|.|||..|:|||||.||.||.:||||||||:..:
  Rat   381 LDNVLLDSEGHIKLTDYGMCKEGLRPGDTTSTFCGTPNYIAPEILRGEDYGFSVDWWALGVLMFE 445

  Fly   348 MLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEV--------QHL 404
            |:..:||                         ..|.|...:.|.::||:|.:.:        :.|
  Rat   446 MMAGRSP-------------------------FDIVGSSDNPDQNTEDYLFQVILEKQIRIPRSL 485

  Fly   405 THEGRDVLRKLLTIEPRQRI 424
            :.:...||:..|..:|::|:
  Rat   486 SVKAASVLKSFLNKDPKERL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	STKc_AGC	167..>354	CDD:270693	76/190 (40%)
Prkci	NP_114448.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		Regulatory domain. /evidence=ECO:0000250	2..253
		Required for interaction with RAB2. /evidence=ECO:0000250	2..28
		PB1_aPKC	26..108	CDD:99725
		Interaction with PARD6A. /evidence=ECO:0000250	72..91
		Pseudosubstrate. /evidence=ECO:0000250	125..134
		C1_aPKC	139..193	CDD:410344
		STKc_aPKC_iota	233..596	CDD:270769	93/280 (33%)