DRSC/TRiP Functional Genomics Resources

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Protein Alignment S6KL and STK32B

DIOPT Version :9

Sequence 1:NP_524861.2 Gene:S6KL / 45970 FlyBaseID:FBgn0283473 Length:483 Species:Drosophila melanogaster
Sequence 2:NP_060871.1 Gene:STK32B / 55351 HGNCID:14217 Length:414 Species:Homo sapiens


Alignment Length:386 Identity:112/386 - (29%)
Similarity:179/386 - (46%) Gaps:73/386 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   133 GKTQWHRPLTNSIFNSHFKETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLI 197
            |....|:|   .:|:.:  |....|.::|...:.||:||.|. :..|.|..:.||:|.:.|.|.|
Human     2 GGNHSHKP---PVFDEN--EEVNFDHFQILRAIGKGSFGKVC-IVQKRDTKKMYAMKYMNKQKCI 60

  Fly   198 EDNSVRQIKDEADIQKVCGHHPFIVKQIDLW---QNRHNLHILSEYVPNGEL---FSKITHFSID 256
            |.:.||.:..|..|.:.. .|||:|   :||   |:..::.::.:.:..|:|   ..:..||:..
Human    61 ERDEVRNVFRELQIMQGL-EHPFLV---NLWYSFQDEEDMFMVVDLLLGGDLRYHLQQNVHFTEG 121

  Fly   257 LVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKY 321
            .|:|||.|:||||::|....||:||.||:||||.|..|:.:|||.::..:|......:|.||..|
Human   122 TVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGAERASSMAGTKPY 186

  Fly   322 MAPEIL-----CGEPYGHAVDWWALGVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQ 381
            ||||:.     .|..|.:.||||:||:.|.::|....| .:.|      ||.|.|.:.|.     
Human   187 MAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRP-YEIH------SVTPIDEILNM----- 239

  Fly   382 INGCLQDSDGDSEDFLPEEVQHLTHEGRD---VLRKLLTIEPRQRIRSVMALQRIAIYKDYN--- 440
                          |..|.|.:.:...:.   :||||||.:|..|:.|:..:|.:....|.|   
Human   240 --------------FKVERVHYSSTWCKGMVALLRKLLTKDPESRVSSLHDIQSVPYLADMNWDA 290

  Fly   441 ----------LSSKQLLSLSP----REIIA------RDGIRIYEDRHFDQLTNQCAIDAFL 481
                      :.:|..|:..|    .|:|.      :...|:.::|..|...:.|.::..|
Human   291 VFKKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKDSCPLNGHL 351

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
S6KLNP_524861.2 S_TKc 159..431 CDD:214567 93/285 (33%)
STKc_AGC 167..>354 CDD:270693 73/197 (37%)
STK32BNP_060871.1 STKc_Yank1 22..283 CDD:270730 94/291 (32%)
S_TKc 23..270 CDD:214567 91/277 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 374..396
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0598
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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