Protein Alignment S6KL and STK32B

DIOPT Version :10

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_047271880.1
• Gene: STK32B / 55351
• HGNCID: 14217
• Length: 502
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 125/463 - (26%)
• Similarity: 199/463 - (42%)
• Gaps: 109/463 - (23%)

  Fly    72 SHPPGDEEQPVQSQQQQLSTWSLGSLSG-GRLNWSFSGARNSFRHRNKATRKSLTS--------- 126
            :.|||           ::.|..|..... |...||...   ..|..::..|.|:.:
Human    33 ARPPG-----------RVGTGILSDTKAPGSPQWSRDA---ELRSGHRCPRPSIANQIWDFLIAG 83

  Fly   127 ----LHGSRRGK--TQWHRPLTNSIFNSHFKETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQC 185
                :.||.|..  |:|     |:....:|      |.::|...:.||:||.|. :..|.|..:.
Human    84 AELVISGSPRPSMDTEW-----NTFRRFNF------DHFQILRAIGKGSFGKVC-IVQKRDTKKM 136

  Fly   186 YALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLW---QNRHNLHILSEYVPNGEL- 246
            ||:|.:.|.|.||.:.||.:..|..|.:.. .|||:|   :||   |:..::.::.:.:..|:|
Human   137 YAMKYMNKQKCIERDEVRNVFRELQIMQGL-EHPFLV---NLWYSFQDEEDMFMVVDLLLGGDLR 197

  Fly   247 --FSKITHFSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLG 309
              ..:..||:...|:|||.|:||||::|....||:||.||:||||.|..|:.:|||.::..:|..
Human   198 YHLQQNVHFTEGTVKLYICELALALEYLQRYHIIHRDIKPDNILLDEHGHVHITDFNIATVVKGA 262

  Fly   310 ANTRTMCGTFKYMAPEIL-----CGEPYGHAVDWWALGVIACQMLTQKSPNIKRHLLRRRESVEP 369
            ....:|.||..|||||:.     .|..|.:.||||:||:.|.::|....| .:.|      ||.|
Human   263 ERASSMAGTKPYMAPEVFQVYMDRGPGYSYPVDWWSLGITAYELLRGWRP-YEIH------SVTP 320

  Fly   370 EDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGRD---VLRKLLTIEPRQRIRSVMALQ 431
            .|.:.|.                   |..|.|.:.:...:.   :||||||.:|..|:.|:..:|
Human   321 IDEILNM-------------------FKVERVHYSSTWCKGMVALLRKLLTKDPESRVSSLHDIQ 366

  Fly   432 RIAIYKDYN-------------LSSKQLLSLSP----REIIA------RDGIRIYEDRHFDQLTN 473
            .:....|.|             :.:|..|:..|    .|:|.      :...|:.::|..|...:
Human   367 SVPYLADMNWDAVFKKALMPGFVPNKGRLNCDPTFELEEMILESKPLHKKKKRLAKNRSRDGTKD 431

  Fly   474 QCAIDAFL 481
            .|.::..|
Human   432 SCPLNGHL 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	STKc_AGC	167..>354	CDD:270693	73/197 (37%)
STK32B	XP_047271880.1	STKc_Yank1	110..371	CDD:270730	94/291 (32%)