Protein Alignment S6KL and Sgk3

DIOPT Version :9

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001032848.1
• Gene: Sgk3 / 170755
• MGIID: 2182368
• Length: 496
• Species: Mus musculus
• Alignment Length: 376
• Identity: 114/376 - (30%)
• Similarity: 177/376 - (47%)
• Gaps: 58/376 - (15%)

  Fly   111 NSFRHRNKAT----RKSLTSLHGSRR----GKTQWHRPLTNSIFNSHFKETSKNDLYRIDHLVAK 167
            :|.||::..:    .:|.:..|.:.|    |.|.          |.|.|.|..:.|    .::.|
Mouse   120 DSPRHQSDPSEDEDERSTSKPHSTSRNINLGPTG----------NPHAKPTDFDFL----KVIGK 170

  Fly   168 GAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLWQNRH 232
            |:||.|.....|.| .:.||:|||:|..::.....:.|..|.::......|||:|.....:|...
Mouse   171 GSFGKVLLAKRKLD-GKFYAVKVLQKKIVLNRKEQKHIMAERNVLLKNVKHPFLVGLHYSFQTTE 234

  Fly   233 NLHILSEYVPNGELFSKITH---FSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLTEQFH 294
            .|:.:.::|..||||..:..   |.....|.|..|||.||.:||:..|:|||.|||||||....|
Mouse   235 KLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEIASALGYLHSIKIVYRDLKPENILLDSMGH 299

  Fly   295 IKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWALGVIACQMLTQKSPNIKR 358
            :.||||||.| .:.:...|.|.|||.:|:|||::..:||.:.||||.||.:..:||....|...|
Mouse   300 VVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCR 364

  Fly   359 -------HLLRRRESVEPEDGLS-NAPSIAQ--INGCLQDSDGDSEDFLPEEVQ-HLTHEG---R 409
                   ::|.:..::.|  |:| .|.||.:  :....|:..|..||||  |:| |...|.   .
Mouse   365 DVAEMYDNILHKPLNLRP--GVSLTAWSILEELLEKNRQNRLGAKEDFL--EIQNHPFFESLSWT 425

  Fly   410 DVLRKLL------TIEPRQRIRSVMAL-------QRIAIYKDYNLSSKQLL 447
            |:::|.:      .:.....||:..|:       ..:.:..||::.:..:|
Mouse   426 DLVQKKIPPPFNPNVAGPDDIRNFDAVFTEETVPYSVCVSSDYSIVNASVL 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	S_TKc	159..431	CDD:214567	98/302 (32%)
		STKc_AGC	167..>354	CDD:270693	74/190 (39%)
Sgk3	NP_001032848.1	PX_CISK	12..120	CDD:132780	114/376 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..157		9/45 (20%)
		S_TKc	162..419	CDD:214567	93/265 (35%)
		STKc_SGK3	165..490	CDD:270755	102/321 (32%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		1/9 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810