Protein Alignment S6KL and RSKR

DIOPT Version :10

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001167574.1
• Gene: RSKR / 124923
• HGNCID: 26314
• Length: 410
• Species: Homo sapiens
• Alignment Length: 356
• Identity: 119/356 - (33%)
• Similarity: 177/356 - (49%)
• Gaps: 43/356 - (12%)

  Fly   136 QWHRPLTNSIFNSHF--KETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQ--CYALKVLKKSKL 196
            :|..|...::|...|  :........:|..|||||:||.|.||   .|.:|  .:|:||:.|.|:
Human    82 EWPVPQFINLFLPEFPIRPIRGQQQLKILGLVAKGSFGTVLKV---LDCTQKAVFAVKVVPKVKV 143

  Fly   197 IEDNSVRQIKDEADIQKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNG--ELFSKITHFSIDLVR 259
            ::.::|||.|:|..||:.. :|||:....|.||.:.:|.|:..|....  .|:|.:..|....:|
Human   144 LQRDTVRQCKEEVSIQRQI-NHPFVHSLGDSWQGKRHLFIMCSYCSTDLYSLWSAVGCFPEASIR 207

  Fly   260 LYIGEIALALDFLHNAGIIYRDAKPENILLTEQFHIKLTDFGLSKWLKLGANTRTMCGTFKYMAP 324
            |:..|:.|.|.:||:.||::||.|.|||||.|:.|:||||||||:.:..||...|:|||.:||||
Human   208 LFAAELVLVLCYLHDLGIMHRDVKMENILLDERGHLKLTDFGLSRHVPQGAQAYTICGTLQYMAP 272

  Fly   325 EILCGEPYGHAVDWWALGVIACQMLTQKSPNIKRHLLRRRESVEPEDGLSNAPSIAQINGCLQDS 389
            |:|.|.||.||.|||:|||:...:.|.|.|     :...|:.|         ..:|.:.    .|
Human   273 EVLSGGPYNHAADWWSLGVLLFSLATGKFP-----VAAERDHV---------AMLASVT----HS 319

  Fly   390 DGDSEDFLPEEVQHLTHEGRDVLRKLLTIEPRQRIRSVMALQRIAIYK----DYNLSSKQLLSLS 450
            |.:....|.:.:..|.||       ||...|..|:|.:...|....::    |..|..||.::..
Human   320 DSEIPASLNQGLSLLLHE-------LLCQNPLHRLRYLHHFQVHPFFRGVAFDPELLQKQPVNFV 377

  Fly   451 PREIIARDGIRIYEDRHFDQLTNQCAIDAFL 481
            ......:....  |...||..  .|.:::||
Human   378 TETQATQPSSA--ETMPFDDF--DCDLESFL 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	STKc_AGC	167..>354	CDD:270693	85/190 (45%)
RSKR	NP_001167574.1	STKc_AGC	115..359	CDD:270693	101/272 (37%)