Protein Alignment S6KL and SGK2

DIOPT Version :9

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001186193.1
• Gene: SGK2 / 10110
• HGNCID: 13900
• Length: 367
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 94/274 - (34%)
• Similarity: 131/274 - (47%)
• Gaps: 45/274 - (16%)

  Fly   164 LVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADIQKVCGHHPFIVKQIDLW 228
            ::.||.:|.|.....||| ...||:|||:|..:::......|..|..:......|||:|.....:
Human    40 VIGKGNYGKVLLAKRKSD-GAFYAVKVLQKKSILKKKEQSHIMAERSVLLKNVRHPFLVGLRYSF 103

  Fly   229 QNRHNLHILSEYVPNGELF---SKITHFSIDLVRLYIGEIALALDFLHNAGIIYRDAKPENILLT 290
            |....|:.:.:||..||||   .:...|.....|.|..|:|.|:.:||:..|||||.|||||||.
Human   104 QTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEVASAIGYLHSLNIIYRDLKPENILLD 168

  Fly   291 EQFHIKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCGEPYGHAVDWWALGVIACQMLTQKSP 354
            .|.|:.||||||.| .::....|.|.|||.:|:|||:|..|||..|||||.||.:..:||....|
Human   169 CQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAPEVLRKEPYDRAVDWWCLGAVLYEMLHGLPP 233

  Fly   355 NIKRHLLRRRESV--EPEDGLSNAPSIAQINGCLQDSDGDSEDFLPEEVQHLTHEGR-----DVL 412
            ...:.:.:..|::  :|          .||.|                       ||     |:|
Human   234 FYSQDVSQMYENILHQP----------LQIPG-----------------------GRTVAACDLL 265

  Fly   413 RKLLTIEPRQRIRS 426
            :.||..:.|||:.|
Human   266 QSLLHKDQRQRLGS 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	S_TKc	159..431	CDD:214567	94/274 (34%)
		STKc_AGC	167..>354	CDD:270693	78/190 (41%)
SGK2	NP_001186193.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		STKc_SGK2	39..359	CDD:270754	94/274 (34%)
		Nuclear localization signal. /evidence=ECO:0000250	68..78		1/9 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810