Protein Alignment S6KL and C8orf44-SGK3

DIOPT Version :9

• Sequence 1: NP_524861.2
• Gene: S6KL / 45970
• FlyBaseID: FBgn0283473
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_001191102.1
• Gene: C8orf44-SGK3 / 100533105
• HGNCID: 48354
• Length: 496
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 97/271 - (35%)
• Similarity: 140/271 - (51%)
• Gaps: 23/271 - (8%)

  Fly   147 NSHFKETSKNDLYRIDHLVAKGAFGVVFKVSSKSDISQCYALKVLKKSKLIEDNSVRQIKDEADI 211
            |.|.|.|..:.|    .::.||:||.|.....|.| .:.||:|||:|..::.....:.|..|.::
Human   154 NPHAKPTDFDFL----KVIGKGSFGKVLLAKRKLD-GKFYAVKVLQKKIVLNRKEQKHIMAERNV 213

  Fly   212 QKVCGHHPFIVKQIDLWQNRHNLHILSEYVPNGELFSKITH---FSIDLVRLYIGEIALALDFLH 273
            ......|||:|.....:|....|:.:.::|..||||..:..   |.....|.|..|||.||.:||
Human   214 LLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEIASALGYLH 278

  Fly   274 NAGIIYRDAKPENILLTEQFHIKLTDFGLSK-WLKLGANTRTMCGTFKYMAPEILCGEPYGHAVD 337
            :..|:|||.|||||||....|:.||||||.| .:.:...|.|.|||.:|:|||::..:||.:.||
Human   279 SIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAPEVIRKQPYDNTVD 343

  Fly   338 WWALGVIACQMLTQKSPNIKR-------HLLRRRESVEPEDGLS-NAPSIAQ--INGCLQDSDGD 392
            ||.||.:..:||....|...|       ::|.:..|:.|  |:| .|.||.:  :....|:..|.
Human   344 WWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRP--GVSLTAWSILEELLEKDRQNRLGA 406

  Fly   393 SEDFLPEEVQH 403
            .||||  |:|:
Human   407 KEDFL--EIQN 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
S6KL	NP_524861.2	S_TKc	159..431	CDD:214567	92/259 (36%)
		STKc_AGC	167..>354	CDD:270693	74/190 (39%)
C8orf44-SGK3	NP_001191102.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		PX_CISK	12..120	CDD:132780
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	121..156		1/1 (100%)
		STKc_SGK3	165..490	CDD:270755	93/260 (36%)
		Nuclear localization signal. /evidence=ECO:0000250	195..205		1/9 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0598
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810