Protein Alignment gwl and Mast3

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_038950759.1
• Gene: Mast3 / 688540
• RGDID: 1587639
• Length: 1337
• Species: Rattus norvegicus
• Alignment Length: 803
• Identity: 142/803 - (17%)
• Similarity: 210/803 - (26%)
• Gaps: 480/803 - (59%)

  Fly    42 PENH---SQNAKLPTIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQV 103
            ||:.   ..:.:.|...||..||.||.||:|.|:| .::.|:::.||||.:.|..:|.:|.:.||
  Rat   387 PESRGLGGPSRRQPCESDFETIKLISNGAYGAVYL-VRHRDTRQRFAIKKINKQNLILRNQIQQV 450

  Fly   104 ITERNALALSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMA 168
            ..||:.|..:.:.|.|.:|.|.::..::.:||||:.|||..:||...|......||.|.||.|:|
  Rat   451 FVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLA 515

  Fly   169 LQYLHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDLEISDLINCSPNLNARTPGQLLS 233
            |:|||.:||||||:||||:|::|.||:||||||||||
  Rat   516 LEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKI---------------------------- 552

  Fly   234 LTSHLSFGSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAINKHSLIMELSDSEGDTSLNDAEKT 298
                                     |:.|:||
  Rat   553 -------------------------GLMSMAT--------------------------------- 559

  Fly   299 SDSKISGVSPFFSAEEANESITHTCTTNVNPQDSSSSCSFHTCNSADLSKCSPPLESKDGAAAGN 363
                                                                             
  Rat   560 ----------------------------------------------------------------- 559

  Fly   364 AIPSKRRVEFVLDAAPCQGCKLAEQDSSNMATNDGKHLPKIDNAIEASFEFSMVRRRSVDERNRI 428
                                                                             
  Rat   560 ----------------------------------------------------------------- 559

  Fly   429 SKGPEDSGVSSRKGDDYSSCHLNLNSESTASSIEKNVDNLSQSKEDFSCSDYSRSYNVTNGNEMS 493
                                                                    |:..|:
  Rat   560 --------------------------------------------------------NLYEGH--- 565

  Fly   494 GINMNSPFRNLSKHFKRPDFLRGMKRKINLVNRSDNMSSMDTDGCSSSNGSTNTGLTQEIEILNI 558
                                                                             
  Rat   566 ----------------------------------------------------------------- 565

  Fly   559 GSSTPKKRKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVANVVFSTPVSSQKLPRRDGGLLGK 623
                                                                             
  Rat   566 ----------------------------------------------------------------- 565

  Fly   624 LKATRFALPLSIENKKREHATADKMSGIQYHLKLSDDPTMSPINHGAGNLPKTPKNVNINTPFRT 688
                       ||...||..
  Rat   566 -----------IEKDAREFV--------------------------------------------- 574

  Fly   689 PKSVRRGARVSNERILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFD 753
                       ::::.|||:|:|||::.:||:|..|||||:||..|||:.|..||..:||:::|.
  Rat   575 -----------DKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFG 628

  Fly   754 NILNKNIEWPEGDEALSVESMEAVELLLTMDPNER---PAAKEVQQMRHFACIDWENIGNTEPPF 815
            .:::..|.||||||||..::.:.:..||...|.:|   ....||:|...|..:||..:...:..|
  Rat   629 QVVSDEIMWPEGDEALPPDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEF 693

  Fly   816 VPTPDNPTDTGYFDARN-NLQHL 837
            ||..:...||.|||.|: ..:||
  Rat   694 VPQLEAEDDTSYFDTRSERYRHL 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	74/202 (37%)
		S_TKc	57..>205	CDD:214567	70/147 (48%)
		PKc_like	<655..835	CDD:304357	54/183 (30%)
Mast3	XP_038950759.1	DUF1908	89..369	CDD:401031
		STKc_MAST	404..683	CDD:270760	126/751 (17%)
		PDZ_signaling	987..1064	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900