Protein Alignment gwl and Mast1

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_064329.2
• Gene: Mast1 / 56527
• MGIID: 1861901
• Length: 1570
• Species: Mus musculus
• Alignment Length: 794
• Identity: 140/794 - (17%)
• Similarity: 212/794 - (26%)
• Gaps: 476/794 - (59%)

  Fly    46 SQNAKLPTIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQVITERNAL 110
            |:..|.|...||..||.||.||:|.|:| .::.|:::.||:|.:.|..:|.:|.:.|...||:.|
Mouse   365 SKAKKPPGESDFDTIKLISNGAYGAVYL-VRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDIL 428

  Fly   111 ALSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMALQYLHQH 175
            ..:.:.|.|.:|.|.::..::.:||||:.|||..:||...|......||.|.||.|:||:|||.:
Mouse   429 TFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNY 493

  Fly   176 GIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDLEISDLINCSPNLNARTPGQLLSLTSHLSF 240
            ||||||:||||:|::|.||:|||||||||:.                        |:|||::|..
Mouse   494 GIVHRDLKPDNLLITSMGHIKLTDFGLSKMG------------------------LMSLTTNLYE 534

  Fly   241 GSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAINKHSLIMELSDSEGDTSLNDAEKTSDSKISG 305
            |
Mouse   535 G---------------------------------------------------------------- 535

  Fly   306 VSPFFSAEEANESITHTCTTNVNPQDSSSSCSFHTCNSADLSKCSPPLESKDGAAAGNAIPSKRR 370
                                                                             
Mouse   536 ----------------------------------------------------------------- 535

  Fly   371 VEFVLDAAPCQGCKLAEQDSSNMATNDGKHLPKIDNAIEASFEFSMVRRRSVDERNRISKGPEDS 435
                                         |:.|                   |.|
Mouse   536 -----------------------------HIEK-------------------DAR---------- 542

  Fly   436 GVSSRKGDDYSSCHLNLNSESTASSIEKNVDNLSQSKEDFSCSDYSRSYNVTNGNEMSGINMNSP 500
                                                                             
Mouse   543 ----------------------------------------------------------------- 542

  Fly   501 FRNLSKHFKRPDFLRGMKRKINLVNRSDNMSSMDTDGCSSSNGSTNTGLTQEIEILNIGSSTPKK 565
                       :||
Mouse   543 -----------EFL--------------------------------------------------- 545

  Fly   566 RKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVANVVFSTPVSSQKLPRRDGGLLGKLKATRFA 630
                                                                             
Mouse   546 ----------------------------------------------------------------- 545

  Fly   631 LPLSIENKKREHATADKMSGIQYHLKLSDDPTMSPINHGAGNLPKTPKNVNINTPFRTPKSVRRG 695
                                                                             
Mouse   546 ----------------------------------------------------------------- 545

  Fly   696 ARVSNERILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFDNILNKNI 760
                ::::.|||:|:|||::|:||:|..|||||:|:..|||:.|..||..:||:::|..:::.:|
Mouse   546 ----DKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDI 606

  Fly   761 EWPEGDEALSVESMEAVELLLTMDPNER---PAAKEVQQMRHFACIDWENIGNTEPPFVPTPDNP 822
            .||||||||..::...:..||..:|..|   ..|.||:|...|..:||..:...:..|:|..::.
Mouse   607 LWPEGDEALPTDAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESE 671

  Fly   823 TDTGYFDARNNLQH 836
            .||.|||.|::..|
Mouse   672 DDTSYFDTRSDRYH 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	77/202 (38%)
		S_TKc	57..>205	CDD:214567	68/147 (46%)
		PKc_like	<655..835	CDD:304357	54/182 (30%)
Mast1	NP_064329.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	23..80
		DUF1908	61..337	CDD:401031
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	94..117
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	139..171
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	341..377		4/11 (36%)
		STKc_MAST	375..654	CDD:270760	126/751 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	717..885
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	892..911
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..967
		PDZ_signaling	970..1052	CDD:238492
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1061..1186
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1202..1294
		PHA03247	<1205..1566	CDD:223021
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1308..1570

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900