Protein Alignment gwl and Mast3

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_006509770.2
• Gene: Mast3 / 546071
• MGIID: 2683541
• Length: 1336
• Species: Mus musculus
• Alignment Length: 803
• Identity: 142/803 - (17%)
• Similarity: 211/803 - (26%)
• Gaps: 480/803 - (59%)

  Fly    42 PENH---SQNAKLPTIKDFVIIKPISRGAFGKVFLGYKNNDSKRLFAIKVMRKSEMINKNMVSQV 103
            ||:.   ..:.:.|...||..||.||.||:|.|:| .::.|:::.||||.:.|..:|.:|.:.||
Mouse   386 PESRGLGGPSRRKPCESDFETIKLISNGAYGAVYL-VRHRDTRQRFAIKKINKQNLILRNQIQQV 449

  Fly   104 ITERNALALSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSLLAMFGYFDEPTARFYVAEMVMA 168
            ..||:.|..:.:.|.|.:|.|.::..::.:||||:.|||..:||...|......||.|.||.|:|
Mouse   450 FVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLA 514

  Fly   169 LQYLHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDLEISDLINCSPNLNARTPGQLLS 233
            |:|||.:||||||:||||:|::|.||:||||||||||
Mouse   515 LEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKI---------------------------- 551

  Fly   234 LTSHLSFGSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAINKHSLIMELSDSEGDTSLNDAEKT 298
                                     |:.|:||
Mouse   552 -------------------------GLMSMAT--------------------------------- 558

  Fly   299 SDSKISGVSPFFSAEEANESITHTCTTNVNPQDSSSSCSFHTCNSADLSKCSPPLESKDGAAAGN 363
                                                                             
Mouse   559 ----------------------------------------------------------------- 558

  Fly   364 AIPSKRRVEFVLDAAPCQGCKLAEQDSSNMATNDGKHLPKIDNAIEASFEFSMVRRRSVDERNRI 428
                                                                             
Mouse   559 ----------------------------------------------------------------- 558

  Fly   429 SKGPEDSGVSSRKGDDYSSCHLNLNSESTASSIEKNVDNLSQSKEDFSCSDYSRSYNVTNGNEMS 493
                                                                    |:..|:
Mouse   559 --------------------------------------------------------NLYEGH--- 564

  Fly   494 GINMNSPFRNLSKHFKRPDFLRGMKRKINLVNRSDNMSSMDTDGCSSSNGSTNTGLTQEIEILNI 558
                                                                             
Mouse   565 ----------------------------------------------------------------- 564

  Fly   559 GSSTPKKRKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVANVVFSTPVSSQKLPRRDGGLLGK 623
                                                                             
Mouse   565 ----------------------------------------------------------------- 564

  Fly   624 LKATRFALPLSIENKKREHATADKMSGIQYHLKLSDDPTMSPINHGAGNLPKTPKNVNINTPFRT 688
                       ||...||..
Mouse   565 -----------IEKDAREFV--------------------------------------------- 573

  Fly   689 PKSVRRGARVSNERILGTPDYLAPELLLKQGHGPAVDWWALGVCFYEFMTGIPPFNDETPQKVFD 753
                       ::::.|||:|:|||::.:||:|..|||||:||..|||:.|..||..:||:::|.
Mouse   574 -----------DKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFG 627

  Fly   754 NILNKNIEWPEGDEALSVESMEAVELLLTMDPNER---PAAKEVQQMRHFACIDWENIGNTEPPF 815
            .:::..|.||||||||.:::.:.:..||...|.:|   ....||:|...|..:||..:...:..|
Mouse   628 QVVSDEIMWPEGDEALPLDAQDLITRLLRQSPMDRLGTGGTHEVKQHPFFLALDWAGLLRHKAEF 692

  Fly   816 VPTPDNPTDTGYFDARN-NLQHL 837
            ||..:...||.|||.|: ..:||
Mouse   693 VPQLEAEDDTSYFDTRSERYRHL 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	74/202 (37%)
		S_TKc	57..>205	CDD:214567	70/147 (48%)
		PKc_like	<655..835	CDD:304357	54/183 (30%)
Mast3	XP_006509770.2	DUF1908	88..368	CDD:370192
		STKc_MAST	403..682	CDD:270760	126/751 (17%)
		PDZ_signaling	986..1063	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900