Protein Alignment gwl and Mast4

DIOPT Version :9

• Sequence 1: NP_524860.2
• Gene: gwl / 45969
• FlyBaseID: FBgn0260399
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_017171016.1
• Gene: Mast4 / 328329
• MGIID: 1918885
• Length: 2658
• Species: Mus musculus
• Alignment Length: 823
• Identity: 144/823 - (17%)
• Similarity: 220/823 - (26%)
• Gaps: 490/823 - (59%)

  Fly    17 KTPKKTHSLIDSEQLLDKINILTTKPENHSQNAKLPTIKDFVIIKPISRGAFGKVFLGYKNNDSK 81
            :||:...|:..|...|.    |..||..          .||..||.||.||:|.|:. .::.:|:
Mouse   582 ETPEMDESVSSSNTSLR----LRRKPRE----------SDFETIKLISNGAYGAVYF-VRHKESR 631

  Fly    82 RLFAIKVMRKSEMINKNMVSQVITERNALALSRSQFCVSLFYSLQSLSYVYLVMEYMVGGDLKSL 146
            :.||:|.:.|..:|.:|.:.|...||:.|..:.:.|.||::.|.::..::.:||||:.|||..:|
Mouse   632 QRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMYCSFETRRHLCMVMEYVEGGDCATL 696

  Fly   147 LAMFGYFDEPTARFYVAEMVMALQYLHQHGIVHRDIKPDNMLLSSSGHVKLTDFGLSKIDMRRDL 211
            :...|......||.|.||.|:||:|||.:||||||:||||:|::|.||:|||||||||:.
Mouse   697 MKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLVTSMGHIKLTDFGLSKVG----- 756

  Fly   212 EISDLINCSPNLNARTPGQLLSLTSHLSFGSEKKLNDFGSVSSGQNNGMGSVATGTSHLLQAINK 276
                               |:|:|::|..|
Mouse   757 -------------------LMSMTTNLYEG----------------------------------- 767

  Fly   277 HSLIMELSDSEGDTSLNDAEKTSDSKISGVSPFFSAEEANESITHTCTTNVNPQDSSSSCSFHTC 341
                                                                             
Mouse   768 ----------------------------------------------------------------- 767

  Fly   342 NSADLSKCSPPLESKDGAAAGNAIPSKRRVEFVLDAAPCQGCKLAEQDSSNMATNDGKHLPKIDN 406
                                                                      |:.|
Mouse   768 ----------------------------------------------------------HIEK--- 771

  Fly   407 AIEASFEFSMVRRRSVDERNRISKGPEDSGVSSRKGDDYSSCHLNLNSESTASSIEKNVDNLSQS 471
                            |.|
Mouse   772 ----------------DAR---------------------------------------------- 774

  Fly   472 KEDFSCSDYSRSYNVTNGNEMSGINMNSPFRNLSKHFKRPDFLRGMKRKINLVNRSDNMSSMDTD 536
                                                    :||
Mouse   775 ----------------------------------------EFL---------------------- 777

  Fly   537 GCSSSNGSTNTGLTQEIEILNIGSSTPKKRKARSSPIRGVLKVRSLSDDEMPINHLLGPEANVAN 601
                                                                             
Mouse   778 ----------------------------------------------------------------- 777

  Fly   602 VVFSTPVSSQKLPRRDGGLLGKLKATRFALPLSIENKKREHATADKMSGIQYHLKLSDDPTMSPI 666
                                                                             
Mouse   778 ----------------------------------------------------------------- 777

  Fly   667 NHGAGNLPKTPKNVNINTPFRTPKSVRRGARVSNERILGTPDYLAPELLLKQGHGPAVDWWALGV 731
                                             ::::.|||:|:|||::|:||:|..|||||:|:
Mouse   778 ---------------------------------DKQVCGTPEYIAPEVILRQGYGKPVDWWAMGI 809

  Fly   732 CFYEFMTGIPPFNDETPQKVFDNILNKNIEWPEGDEALSVESMEAVELLLTMDPNER---PAAKE 793
            ..|||:.|..||..:||:::|..:::..|.|||.|||...::.|.:.|||..:|.||   ..|.|
Mouse   810 ILYEFLVGCVPFFGDTPEELFGQVISDEINWPEKDEAPPPDAQELITLLLRQNPLERLGTGGAYE 874

  Fly   794 VQQMRHFACIDWENIGNTEPPFVPTPDNPTDTGYFDARNNLQH 836
            |:|.|.|..:||.::...:..|:|..::..||.|||.|:...|
Mouse   875 VKQHRFFRSLDWNSLLRQKAEFIPQLESEDDTSYFDTRSEKYH 917

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gwl	NP_524860.2	STKc_MASTL	52..>255	CDD:270761	73/202 (36%)
		S_TKc	57..>205	CDD:214567	66/147 (45%)
		PKc_like	<655..835	CDD:304357	56/182 (31%)
Mast4	XP_017171016.1	DUF1908	293..569	CDD:370192
		STKc_MAST	607..886	CDD:270760	125/751 (17%)
		PDZ_signaling	1184..1262	CDD:238492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0606
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900